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Ion chromatography on-chip


Murrihy, JP and Breadmore, MC and Tan, A and McEnery, M and Alderman, J and O'Mathuna, C and O'Neill, AP and O'Brien, P and Advoldvic, N and Haddad, PR and Glennon, JD, Ion chromatography on-chip, Journal of Chromatography A, 924, (1-2) pp. 233-238. ISSN 0021-9673 (2001) [Refereed Article]

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DOI: doi:10.1016/S0021-9673(01)00855-X


On-chip separation of inorganic anions by ion-exchange chromatography was realized. Micro separation channels were fabricated on a silicon wafer and sealed with a Pyrex cover plate using standard photolithography, wet and dry chemical etching, and anodic bonding techniques. Quaternary ammonium latex particles were employed for the first time to coat the separation channels on-chip. Owing to the narrow depths of the channels on the chip, 0.510 μm, there were more interactions of the analytes with the stationary phase on the chip than in a 50-μm I.D. capillary. With off-chip injection (20 nl) and UV detection, NO2, NO3, I, and thiourea were separated using 1 mM KCl as the eluent. The linear ranges for NO2 and NO3 are from 5 to 1000 μM with the detection limits of 0.5 μM.

Item Details

Item Type:Refereed Article
Keywords:chip technology, instrumentation, latex nanoparticles, microseparation
Research Division:Chemical Sciences
Research Group:Analytical chemistry
Research Field:Separation science
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the chemical sciences
UTAS Author:Breadmore, MC (Professor Michael Breadmore)
UTAS Author:Haddad, PR (Professor Paul Haddad)
ID Code:22202
Year Published:2001
Web of Science® Times Cited:56
Deposited By:Chemistry
Deposited On:2001-08-01
Last Modified:2012-11-06

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