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Malignant thymic carcinoid is not prevented by transcervical thymectomy in multiple endocrine neoplasia type 1

Citation

Burgess, JR and Giles, N and Shepherd, JJ, Malignant thymic carcinoid is not prevented by transcervical thymectomy in multiple endocrine neoplasia type 1, Clinical Endocrinology, 55, (5) pp. 689-693. ISSN 0300-0664 (2001) [Refereed Article]

DOI: doi:10.1046/j.1365-2265.2001.01348.x

Abstract

Multiple endocrine neoplasia type 1 (MEN 1) is an autosomal dominant tumour syndrome. It is characterized by primary hyperparathyroidism, pituitary neoplasia and foregut lineage neuroendocrine neo-plasia. Malignant thymic carcinoid tumours are an uncommon but important manifestation of MEN 1. Transcervical thymectomy is often advocated as prophylaxis against thymic carcinoids, although there is a paucity of evidence to support the efficacy of this procedure. This is the first report of a malignant thymic carcinoid occurring in an MEN 1 patient following prior parathyroidectomy and transcervical thymectomy. It is concluded that transcervical thymectomy does not reliably provide prophylaxis against thymic carcinoid.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Oncology and Carcinogenesis
Research Field:Oncology and Carcinogenesis not elsewhere classified
Objective Division:Health
Objective Group:Clinical Health (Organs, Diseases and Abnormal Conditions)
Objective Field:Cancer and Related Disorders
Author:Burgess, JR (Professor John Burgess)
Author:Shepherd, JJ (Professor Joseph Shepherd)
ID Code:21786
Year Published:2001
Web of Science® Times Cited:27
Deposited By:Medicine (Discipline)
Deposited On:2001-08-01
Last Modified:2011-09-29
Downloads:0

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