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Pathologic Splenic Rupture as the Presentation of Mantle Cell Lymphoma
journal contribution
posted on 2023-05-16, 12:50 authored by Strickland, A, Marsden, KA, McArdle, J, Raymond LowenthalPathologic splenic rupture in non-Hodgkin's lymphoma (NHL) is a rare event, with 32 cases previously reported. Initial presentation of NHL with this complication is even rarer. We report such a case in an 80-year-old man with mantle cell lymphoma (MCL). It is notable that of the previously reported cases of pathologic rupture, three have occurred in MCL, suggesting that patients with this uncommon subtype of NHL may be particularly vulnerable to pathologic splenic rupture. Following splenectomy the patient's disease behaved in a high-grade fashion. Despite an initially encouraging response, his disease ran an aggressive course and he succumbed within four months. This case demonstrates the presentation of MCL with pathologic splenic rupture, as well as the potentially highly malignant behaviour of the disease.
History
Publication title
Leukemia and LymphomaVolume
41Issue
1-2Pagination
197-201ISSN
1042-8194Department/School
Tasmanian School of MedicinePublisher
Harwood Academic Publishers GmbH, Taylor & Francis GroupPlace of publication
Philadelphia, USARepository Status
- Restricted