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The genetic code as a periodic table: algebraic aspects


Bashford, JD and Jarvis, PD, The genetic code as a periodic table: algebraic aspects, Biosystems, 57, (3) pp. 147-161. ISSN 0303-2647 (2000) [Refereed Article]

DOI: doi:10.1016/S0303-2647(00)00097-6


The systematics of indices of physico-chemical properties of codons and amino acids across the genetic code are examined. Using a simple numerical labelling scheme for nucleic acid bases, A = (-1,0), C = (0,-1) G = (0,1), U = (1,0), data can be fitted as low order polynomials of the six coordinates in the 64-dimensional codon weight space. The work confirms and extends the recent studies by Siemion et al. (1995. BioSystems 36, 231-238) of the conformational parameters. Fundamental patterns in the data such as codon periodicities, and related harmonics and reflection symmetries, are here associated with the structure of the set of basis monomials chosen for fitting. Results are plotted using the Siemion one-step mutation ring scheme, and variants thereof. The connections between the present work, and recent studies of the genetic code structure using dynamical symmetry algebras, are pointed out. (C) 2000 Elsevier Science Ireland Ltd.

Item Details

Item Type:Refereed Article
Research Division:Physical Sciences
Research Group:Other physical sciences
Research Field:Other physical sciences not elsewhere classified
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the physical sciences
UTAS Author:Jarvis, PD (Dr Peter Jarvis)
ID Code:20557
Year Published:2000
Web of Science® Times Cited:25
Deposited By:Physics
Deposited On:2000-08-01
Last Modified:2011-08-04

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