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Pathology of Experimental Toxoplasmosis in Eastern Barred Bandicoots in Tasmania


Bettiol, SS and Obendorf, DL and Nowarkowski, M and Goldsmid, JM, Pathology of Experimental Toxoplasmosis in Eastern Barred Bandicoots in Tasmania, Journal of Wildlife Diseases, 36, (1) pp. 141-144. ISSN 0090-3558 (2000) [Refereed Article]

DOI: doi:10.7589/0090-3558-36.1.141


Wild-caught eastern barred bandicoots (Perameles gunnii) initially seronegative to Toxoplasma gondii, were inoculated orally with approximately 100 T. gondii oocysts. The bandicoots were maintained in indoor pens under laboratory conditions and observed daily. Serial blood samples were tested for agglutinating antibodies to T. gondii. Inoculated bandicoots died 15 and 17 days post infection. A rise in Direct Agglutination Test (DAT) titres was detected at the time of death (1:256, 1:64 respectively). Clinical observations, serological changes, gross findings at necropsy, and histopathological changes were consistent with acute toxoplasmosis. The findings indicate that eastern barred bandicoots are likely to die from primary T. gondii infection, often even before detectable antibodies are produced, reinforcing the significance of toxoplasmosis as a potential contributor to the reduction in numbers of wild populations of eastern barred bandicoots.

Item Details

Item Type:Refereed Article
Research Division:Biological Sciences
Research Group:Microbiology
Research Field:Infectious agents
Objective Division:Health
Objective Group:Public health (excl. specific population health)
Objective Field:Disease distribution and transmission (incl. surveillance and response)
UTAS Author:Bettiol, SS (Dr Silvana Bettiol)
UTAS Author:Obendorf, DL (Dr David Obendorf)
UTAS Author:Nowarkowski, M (Mr Mark Nowarkowski)
UTAS Author:Goldsmid, JM (Professor John Goldsmid)
ID Code:19485
Year Published:2000
Web of Science® Times Cited:18
Deposited By:Pathology
Deposited On:2000-08-01
Last Modified:2001-05-04

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