Because of its simplicity, speed and effectiveness, solid-phase extraction (SPE) has become the preferred technique for concentration of selected analytes prior to chromatographic or electrophoretic analysis. In this review the historical development of SPE is briefly traced. Then the principles of SPE are reviewed in some detail. Numerous references are given on the format, sorbents, elution conditions, online techniques and automation with special emphasis on relatively recent developments. The principles and recent advances in solid-phase microextraction (SPME) are also reviewed. The final section on selected recent applications includes an extensive list of references to work published within the last three years. Future trends and developments are discussed briefly. Copyright (C) 2000 Elsevier Science B.V.

Item Type:	Refereed Article
Research Division:	Chemical Sciences
Research Group:	Analytical Chemistry
Research Field:	Separation Science
Objective Division:	Expanding Knowledge
Objective Group:	Expanding Knowledge
Objective Field:	Expanding Knowledge in the Chemical Sciences
Author:	Fritz, J (Professor Jim Fritz)
Author:	Macka, M (Professor Mirek Macka)
ID Code:	19461
Year Published:	2000
Web of Science® Times Cited:	66
Deposited By:	Chemistry
Deposited On:	2000-08-01
Last Modified:	2011-08-04
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