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Application of high-performance liquid chromatography to the investigation of free radical reactions in biological systems

Citation

Glod, B and Czapski, G and Haddad, PR, Application of high-performance liquid chromatography to the investigation of free radical reactions in biological systems, Trends in Analytical Chemistry, 19, (8) pp. 493-497. ISSN 0165-9936 (2000) [Refereed Article]


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DOI: doi:10.1016/S0165-9936(00)00018-2

Abstract

The determination of free radicals and their reaction products in biological systems is discussed, with an emphasis on the use of liquid chromatographic methods for the analysis. Free radicals formed from oxygen and its reduction products, nitric oxide, and lipid radicals are considered. Whilst reversed-phase high-performance liquid chromatography has found wide application for these analyses, ion-exclusion chromatography also has significant potential and some developments in this area are described.

Item Details

Item Type:Refereed Article
Keywords: High-performance liquid chromatography; Ion exclusion chromatography; Reactive oxygen species; Free radicals; Nitric oxide; Malonyldialdehyde
Research Division:Chemical Sciences
Research Group:Analytical Chemistry
Research Field:Separation Science
Objective Division:Expanding Knowledge
Objective Group:Expanding Knowledge
Objective Field:Expanding Knowledge in the Chemical Sciences
Author:Glod, B (Dr Bronislaw Glod)
Author:Haddad, PR (Professor Paul Haddad)
ID Code:19423
Year Published:2000
Web of Science® Times Cited:15
Deposited By:Chemistry
Deposited On:2000-08-01
Last Modified:2010-02-20
Downloads:0

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