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The effect of levamisole as an adjuvant on the humoral immune response of Atlantic salmon (Salmo salar L.)
journal contribution
posted on 2023-05-16, 12:01 authored by Morrison, RN, Barbara NowakBarbara Nowak, Carson, JPre and post-smolt Atlantic salmon (Salmo salar L.) were administered a levamisole adjuvanted Vibrio anguillarum vaccine by bath or intraperitoneal (IP) injection. A significant serum anti-V. anguillarum antibody response was elicited in groups of fish administered an IP injection of bacterium only. Fish (pre and post-smolt) treated with the levamisole adjuvanted vaccine (IP and bath) showed a suppressed response relative to the respective positive (vaccinated) control groups. No detectable antibody response was elicited in fish not treated or treated with a placebo. Results from this trial suggest that levamisole as an adjuvant has a narrow range of efficacy.
History
Publication title
Bulletin of European Association of Fish PathologistsVolume
20Pagination
101-105ISSN
0108-0288Department/School
Institute for Marine and Antarctic StudiesPublisher
European Association of Fish PathologistsPlace of publication
Aberdeen, ScotlandRepository Status
- Restricted