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The effect of levamisole as an adjuvant on the humoral immune response of Atlantic salmon (Salmo salar L.)

Citation

Morrison, RN and Nowak, BF and Carson, J, The effect of levamisole as an adjuvant on the humoral immune response of Atlantic salmon (Salmo salar L.), Bulletin of European Association of Fish Pathologists, 20, (3) pp. 101-105. ISSN 0108-0288 (2000) [Refereed Article]

Abstract

Pre and post-smolt Atlantic salmon (Salmo salar L.) were administered a levamisole adjuvanted Vibrio anguillarum vaccine by bath or intraperitoneal (IP) injection. A significant serum anti-V. anguillarum antibody response was elicited in groups of fish administered an IP injection of bacterium only. Fish (pre and post-smolt) treated with the levamisole adjuvanted vaccine (IP and bath) showed a suppressed response relative to the respective positive (vaccinated) control groups. No detectable antibody response was elicited in fish not treated or treated with a placebo. Results from this trial suggest that levamisole as an adjuvant has a narrow range of efficacy.

Item Details

Item Type:Refereed Article
Research Division:Agricultural and Veterinary Sciences
Research Group:Fisheries Sciences
Research Field:Fish Pests and Diseases
Objective Division:Animal Production and Animal Primary Products
Objective Group:Fisheries - Aquaculture
Objective Field:Fisheries - Aquaculture not elsewhere classified
Author:Morrison, RN (Dr Richard Morrison)
Author:Nowak, BF (Professor Barbara Nowak)
ID Code:18447
Year Published:2000
Web of Science® Times Cited:6
Deposited By:TAFI - Aquaculture
Deposited On:2000-08-01
Last Modified:2011-09-27
Downloads:0

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