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Iron fortified follow on formula from 9 to 18 months improves iron status but not development or growth: a randomised trial

Citation

Morley, R and Abbott, R and Fairweather-Tait, S and MacFadyen, U and Stephenson, T and Lucas, A, Iron fortified follow on formula from 9 to 18 months improves iron status but not development or growth: a randomised trial, Archives of Disease in Childhood, 81, (3) pp. 247-252. ISSN 0003-9888 (1999) [Refereed Article]

DOI: doi:10.1136/adc.81.3.247

Abstract

Aims - Iron deficiency anaemia is associated, in observational studies, with developmental disadvantage. This study tested the hypothesis that feeding iron supplemented formula from 9 to 18 months of age would improve developmental performance. Subjects and methods - 493 healthy children aged 9 months being fed pasteurised cows' milk were recruited from three UK centres. They were randomised to: cows' milk as before, formula containing 0.9 mg/litre iron, or formula containing 1.2 mg/litre irons until 18 months of age. Bayley mental and psychomotor developmental indices were measured at 18 months, as were growth and haematological indices. Results - Children fed iron fortified formula had higher plasma ferritin concentrations, but there were no significant intergroup differences in development or growth. Conclusions - There are no developmental or growth advantages in children given iron supplemented formulas but a benefit for a minority who were anaemic, or the possibility that a benefit may emerge at a later age, cannot be excluded.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Public Health and Health Services
Research Field:Epidemiology
Objective Division:Health
Objective Group:Specific Population Health (excl. Indigenous Health)
Objective Field:Child Health
Author:Morley, R (Dr Ruth Morley)
ID Code:17804
Year Published:1999
Web of Science® Times Cited:68
Deposited By:Menzies Centre
Deposited On:1999-08-01
Last Modified:2011-09-21
Downloads:0

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