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Dexamethasone suppression test reversal in rapid transcranial magnetic stimulation-treated depression


Reid, P and Pridmore, S, Dexamethasone suppression test reversal in rapid transcranial magnetic stimulation-treated depression, Australian and New Zealand Journal of Psychiatry, 33, (2) pp. 274-277. ISSN 0004-8674 (1999) [Refereed Article]

DOI: doi:10.1046/j.1440-1614.1999.00550.x


Objective: The aim of this paper is to report the effect of rapid transcranial magnetic stimulation (rTMS) on the mood and dexamethasone suppression test (DST) of a patient with major depressive disorder (DSM-IV). Clinical picture: A 36-year-old woman with a past history of prolactinoma and recurrent major depressive disorder presented with major depression on three separate occasions over a 3-month period. DST was positive on each occasion. Treatment: During each episode, a course of rTMS was given. Courses varied from seven to 13 once-daily treatment sessions depending on clinical response. These treatment sessions were 20 trains of 10 Hz for 5 s at 100% of motor threshold. Outcome: Remission was achieved, psychiatric rating scales improved and the DST status converted from positive to negative. There were no side effects. Conclusion: DST status in major depressive disorder can be converted from positive to negative by rTMS. This so far unreported observation increases our knowledge of rTMS.

Item Details

Item Type:Refereed Article
Research Division:Health Sciences
Research Group:Health services and systems
Research Field:Mental health services
Objective Division:Health
Objective Group:Public health (excl. specific population health)
Objective Field:Mental health
UTAS Author:Pridmore, S (Professor Saxby Pridmore)
ID Code:17661
Year Published:1999
Web of Science® Times Cited:25
Deposited By:Psychiatry
Deposited On:1999-08-01
Last Modified:2000-05-25

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