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Critical comparison of retention models for optimisation of the separation of anions in ion chromatography. III.Anion chromatography using hydroxide eluents on a Dionex AS11 stationary phase
journal contribution
posted on 2023-05-16, 11:37 authored by Madden, JE, Avdalovic, N, Jackson, PE, Paul HaddadPaul HaddadThree ion chromatography (IC) retention models, namely the linear solvent strength model (LSSM), empirical end points model (EEPM) and three-point curve fitting using DryLab from LC Resources were evaluated in terms of their ability to predict retention factors for inorganic anions separated on a Dionex AS11 column using electrolytically generated hydroxide eluents. Extensive experimental retention data were gathered for 21 anions (fluoride, acetate, formate, bromate, chloride, nitrite, methanesulfonate, bromide, chlorate, nitrate, iodide, thiocyanate, succinate, sulfate, tartrate, oxalate, tungstate, phthalate, chromate, thiosulfate and phosphate) using hydroxide eluents of varying concentration. Although the purely theoretical LSSM was found to give adequate performance, the EEPM (in which a linear relationship is assumed between the logarithm of retention factor and the logarithm of eluent strength, but the slope is determined empirically) and DryLab performed better, with DryLab giving the best accuracy and precision of the three models. The EEPM and DryLab were also shown to have advantages in terms of their low knowledge requirements and ease of solution. Compared with IC using dual eluent species, the retention behaviour in IC using single eluent species was found to be easier to model by both theoretical and empirical approaches.
History
Publication title
Journal of Chromatography AVolume
837Issue
1-2Pagination
65-74ISSN
0021-9673Department/School
School of Natural SciencesPublisher
Elsevier SciencePlace of publication
The NetherlandsRights statement
The definitive version is available at http://www.sciencedirect.comRepository Status
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