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Vascular control of nutrient delivery by flow distribution within muscle: implications for exercise and post-exercise muscle metabolism

Citation

Clark, MG and Rattigan, S and Newman, JMB and Eldershaw, TPD, Vascular control of nutrient delivery by flow distribution within muscle: implications for exercise and post-exercise muscle metabolism, International Journal of Sports Medicine, 19, (6) pp. 391-400. ISSN 0172-4622 (1998) [Refereed Article]

DOI: doi:10.1055/s-2007-971935

Abstract

There is evidence for non-nutritive flow routes within, or associated with, skeletal muscle. Large capillary-like structures are possible candidates. The proportion of flow distributed between nutritive and non-nutritive routes appears to be tightly regulated and can control muscle metabolism and contraction by regulating delivery and product removal. The portion of flow that is carried by the non-nutritive routes at rest affords a flow reserve for amplifying nutrient delivery as muscle begins to work and may determine post-exercise metabolism. Inappropriate signals, however, may diminish nutritive flow to the detriment of muscle performance and post-exercise recovery. New technologies should allow the identification of the non-nutritive routes.

Item Details

Item Type:Refereed Article
Research Division:Medical and Health Sciences
Research Group:Medical Physiology
Research Field:Systems Physiology
Objective Division:Health
Objective Group:Other Health
Objective Field:Health not elsewhere classified
Author:Clark, MG (Professor Michael Clark)
Author:Rattigan, S (Professor Stephen Rattigan)
Author:Newman, JMB (Dr John Newman)
Author:Eldershaw, TPD (Mr Tristram Eldershaw)
ID Code:15574
Year Published:1998
Web of Science® Times Cited:19
Deposited By:Biochemistry
Deposited On:1998-08-01
Last Modified:2011-08-10
Downloads:0

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