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Characterization and genomic analysis of a novel Synechococcus phage S-H9–2 belonging to Bristolvirus genus isolated from the Yellow Sea


Luo, L and Ma, X and Guo, R and Jiang, T and Wang, T and Shao, H and He, H and Wang, H and Liang, Y and McMinn, A and Guo, C and Wang, M, Characterization and genomic analysis of a novel Synechococcus phage S-H9-2 belonging to Bristolvirus genus isolated from the Yellow Sea, Virus Research, 328 Article 199072. ISSN 0168-1702 (2023) [Refereed Article]

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© 2023 The Authors. Published by Elsevier B.V.

DOI: doi:10.1016/j.virusres.2023.199072


Cyanophages are known to influence the population dynamics and community structure of cyanobacteria and thus play an important role in biogeochemical cycles in aquatic ecosystems. In this study, a novel Synechococcus phage S-H9–2 infecting Synechococcus sp. WH 8102 was isolated from the coastal water of the Yellow Sea. Synechococcus phage S-H9–2 contains a 187,320 bp genome of double-stranded DNA with a G + C content of 40.3%, 202 potential open reading frames (ORFs), and 15 tRNAs. Phylogenetic analysis and nucleotide-based intergenomic similarity suggest that Synechococcus phage S-H9–2 belongs to the Bristolvirus genus under the family Kyanoviridae. Homologs of the S-H9–2 open reading frame can be found in a variety of marine environments, as shown by the results of mapping the genome sequence of S-H9–2 to the Global Ocean Viromes 2.0 dataset. The presence of auxiliary metabolic genes (AMGs) related to photosynthesis, carbon metabolism, and phosphorus assimilation, as well as phylogenetic relationships based on complete genome sequences, reflect the mechanism of phage-host interaction and host-specific strategies for adaptation to environmental conditions. This study enriches the current genomic database of cyanophage and contributed to our understanding of the virus-host interactions and their adaption to the environment.

Item Details

Item Type:Refereed Article
Keywords:Synechcoccus, Bristolvirus, Yellow Sea, cyanophage, genomic and phylogenetic analysis, auxiliary metabolic genes
Research Division:Biological Sciences
Research Group:Genetics
Research Field:Genomics
Objective Division:Environmental Management
Objective Group:Coastal and estuarine systems and management
Objective Field:Coastal or estuarine biodiversity
UTAS Author:McMinn, A (Professor Andrew McMinn)
ID Code:155520
Year Published:2023
Deposited By:Ecology and Biodiversity
Deposited On:2023-02-27
Last Modified:2023-03-23

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