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Key considerations to reduce or address respondent burden in patient-reported outcome (PRO) data collection


Aiyegbusi, OL and Roydhouse, J and Cruz Rivera, S and Kamudoni, P and Schache, P and Wilson, R and Stephens, R and Calvert, M, Key considerations to reduce or address respondent burden in patient-reported outcome (PRO) data collection, Nature Communications, 13, (1) Article 6026. ISSN 2041-1723 (2022) [Refereed Article]

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Copyright Statement

2022. The Authors. This article is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) License (, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

DOI: doi:10.1038/s41467-022-33826-4


Patient-reported outcomes (PROs) are used in clinical trials to provide evidence of the benefits and risks of interventions from a patient perspective and to inform regulatory decisions and health policy. The collection of PROs in routine practice can facilitate monitoring of patient symptoms; identification of unmet needs; prioritisation and/or tailoring of treatment to the needs of individual patients and inform value-based healthcare initiatives. However, respondent burden needs to be carefully considered and addressed to avoid high rates of missing data and poor reporting of PRO results, which may lead to poor quality data for regulatory decision making and/or clinical care.

Item Details

Item Type:Refereed Article
Keywords:patient-reported outcomes, respondent burden, data collection
Research Division:Health Sciences
Research Group:Health services and systems
Research Field:Health services and systems not elsewhere classified
Objective Division:Health
Objective Group:Evaluation of health and support services
Objective Field:Evaluation of health outcomes
UTAS Author:Roydhouse, J (Dr Jessica Roydhouse)
ID Code:153890
Year Published:2022
Deposited By:Menzies Institute for Medical Research
Deposited On:2022-10-13
Last Modified:2022-11-28

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