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Development and formulation of the classification criteria for osteoarthritis


Huang, C and Zhang, Z and Chen, Y and Zhang, Y and Xing, D and Zhao, L and Lin, J and Mei, Y and Lin, H-Y and Zheng, Y and Tsai, W-C and Liu, S and Jiang, Q and Liu, Y and Chen, J and Ye, Z and Chen, M and Chen, Y and Chu, C-Q and Gao, M and He, L and Jin, L and Wu, L and Xu, J and Yang, P and Zhang, X and Jiang, Q and Lei, G and Li, M and Yang, W and Gu, X and Zhou, Y and He, D and Liu, W and Zhang, W and Ding, C and Zeng, X, on behalf of the COACH Group, Development and formulation of the classification criteria for osteoarthritis, Annals of Translational Medicine, 8, (17) Article 1068. ISSN 2305-5839 (2020) [Refereed Article]

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Copyright Statement

2020 Annals of Translational Medicine. All rights reserved. This is an Open Access article distributed in accordance with the Creative Commons Attribution-Non Commercial-No Derivs 4.0 International License (CC BY-NC-ND 4.0),

DOI: doi:10.21037/atm-20-4673


Background: The classification criteria of osteoarthritis (OA) is lack of the support of relevant research evidence and there is no standardized protocol for detailed steps of the development or clinical verification of classification criteria has yet been established. This study aims to describe the development process of the Categorization of Osteoarthritis CHecklist (COACH), which is designed to choose the precise treatment option for patients with OA.

Methods: A multidisciplinary panel was established to gather opinions. We conducted questionnaire survey and literature review to generate and COACH Panel members were invited to review the drafted classification criteria and optimize classification criteria. The final list of items was discussed and reached the agreement by the core group of the panel.

Results: Thirty-six experts participated in COACH Panel including rheumatologist (80.6%; 29/36), orthopedist (13.9%; 5/36), methodologist (2.8%; 1/36) and rehabilitation physician (2.8%; 1/36) for classification factors generating and optimizing. The main body of the final classification criteria consists of six types of OA pathogenesis, eight types of medical findings (which can be grouped into two categories), and six types of the location. The final criteria include load-based type, structure-based type, inflammation-based type, metabolic-based type, systemic factor based type and mixed type.

Conclusions: COACH can better help clinicians quickly classify OA patients and help to choose the best treatment option from the aspects of types, findings and locations. What's more, the classification criteria are also helpful to promote the basic medical research and targeted prevention of OA.

Item Details

Item Type:Refereed Article
Keywords:osteoarthritis (OA), classification, classification factors, survey, literature review
Research Division:Biomedical and Clinical Sciences
Research Group:Clinical sciences
Research Field:Rheumatology and arthritis
Objective Division:Health
Objective Group:Clinical health
Objective Field:Treatment of human diseases and conditions
UTAS Author:Ding, C (Professor Chang-Hai Ding)
ID Code:152847
Year Published:2020
Web of Science® Times Cited:2
Deposited By:Menzies Institute for Medical Research
Deposited On:2022-08-25
Last Modified:2022-11-03

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