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Analytical separation of carcinogenic and genotoxic alkenylbenzenes in foods and related products (2010-2020)


Dang, NHP and Quirino, JP, Analytical separation of carcinogenic and genotoxic alkenylbenzenes in foods and related products (2010-2020), Toxins, 13, (6) pp. 1-25. ISSN 2072-6651 (2021) [Refereed Article]


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Copyright 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://

DOI: doi:10.3390/toxins13060387


Alkenylbenzenes are potentially toxic (genotoxic and carcinogenic) compounds present in plants such as basil, tarragon, anise star and lemongrass. These plants are found in various edible consumer products, e.g., popularly used to flavour food. Thus, there are concerns about the possible health consequences upon increased exposure to alkenylbenzenes especially due to food intake. It is therefore important to constantly monitor the amounts of alkenylbenzenes in our food chain. A major challenge in the determination of alkenylbenzenes in foods is the complexity of the sample matrices and the typically low amounts of alkenylbenzenes present. This review will therefore discuss the background and importance of analytical separation methods from papers reported from 2010 to 2020 for the determination of alkenylbenzenes in foods and related products. The separation techniques commonly used were gas and liquid chromatography (LC). The sample preparation techniques used in conjunction with the separation techniques were various variants of extraction (solvent extraction, liquid-liquid extraction, liquid-phase microextraction, solid phase extraction) and distillation (steam and hydro-). Detection was by flame ionisation and mass spectrometry (MS) in gas chromatography (GC) while in liquid chromatography was mainly by spectrophotometry.

Item Details

Item Type:Refereed Article
Keywords:alkenylbenzenes; food; liquid chromatography; gas chromatography; capillary electrophoresis; sample preparation
Research Division:Chemical Sciences
Research Group:Analytical chemistry
Research Field:Separation science
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the chemical sciences
UTAS Author:Dang, NHP (Ms Huynh Ngoc Phuong Dang)
UTAS Author:Quirino, JP (Associate Professor Lito Quirino)
ID Code:152491
Year Published:2021
Web of Science® Times Cited:5
Deposited By:Chemistry
Deposited On:2022-08-19
Last Modified:2022-09-05
Downloads:8 View Download Statistics

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