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Can we replace liquid chromatography with the greener capillary electrophoresis?


Ranasinghe, M and Quirino, JP, Can we replace liquid chromatography with the greener capillary electrophoresis?, Current Opinion in Green and Sustainable Chemistry, 31 Article 100515. ISSN 2452-2236 (2021) [Refereed Article]

Copyright Statement

2021 Published by Elsevier B.V.

DOI: doi:10.1016/j.cogsc.2021.100515


Liquid phase separations are major players in chemical analysis. Liquid chromatography (LC) uses mobile phases that typically contain organic solvents. LC could generate significant volumes of chemical waste especially in routine analysis where many samples are processed. An alternative to LC is capillary electrophoresis (CE) which uses smaller volumes of background solution/mobile phase. In this review, we compared the analytical performance of different modes of LC and CE for the analysis of the same compounds. The modes selected were reversed phase LC versus capillary zone electrophoresis and electrokinetic chromatography, chiral LC versus chiral electrokinetic chromatography, and size exclusion chromatography versus capillary gel electrophoresis. Articles covered were published from 2018 to 2020. We will recommend if CE can replace LC for some applications.

Item Details

Item Type:Refereed Article
Keywords:solid-phase extraction, electrochromatography, spectrometry, principles, separation, chemistry, markets
Research Division:Chemical Sciences
Research Group:Inorganic chemistry
Research Field:Inorganic chemistry not elsewhere classified
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the chemical sciences
UTAS Author:Ranasinghe, M (Mrs Muhandiramge Ranasinghe)
UTAS Author:Quirino, JP (Associate Professor Lito Quirino)
ID Code:152441
Year Published:2021
Web of Science® Times Cited:15
Deposited By:Physics
Deposited On:2022-08-19
Last Modified:2022-09-15

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