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Enantioselective synthesis of 5- to 16-membered N-heterocycles via a Pd-catalyzed cascade

Citation

Hawkins, BC and Bissember, AC, Enantioselective synthesis of 5- to 16-membered N-heterocycles via a Pd-catalyzed cascade, Chem Catalysis, 2, (8) pp. 1849-1850. ISSN 2667-1093 (2022) [Contribution to Refereed Journal]


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DOI: doi:10.1016/j.checat.2022.07.015

Abstract

In this issue of Chem Catalysis, Huang and co-workers demonstrate the synthetic utility of an enantioselective palladium-catalyzed cascade reaction that is underpinned by a σ-bond C-N metathesis/isomerization/Csp3-Pd migratory insertion sequence. The capacity of this methodology to reliably and stereoselectively construct saturated 5-membered to macrocyclic N-heterocycles underscores the broad scope and impressive flexibility of this approach.

Item Details

Item Type:Contribution to Refereed Journal
Research Division:Chemical Sciences
Research Group:Organic chemistry
Research Field:Organic chemical synthesis
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the chemical sciences
UTAS Author:Bissember, AC (Associate Professor Alex Bissember)
ID Code:152440
Year Published:2022
Deposited By:Chemistry
Deposited On:2022-08-19
Last Modified:2023-02-06
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