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Consensus guidelines for the diagnosis and management of invasive candidiasis in haematology, oncology and intensive care settings, 2021

Citation

Keighley, C and Cooley, L and Morris, AJ and Ritchie, D and Clark, JE and Boan, P and Worth, LJ, Consensus guidelines for the diagnosis and management of invasive candidiasis in haematology, oncology and intensive care settings, 2021, Internal Medicine Journal, 51, (S7) pp. 89-117. ISSN 1444-0903 (2021) [Refereed Article]

Copyright Statement

2021 Royal Australasian College of Physicians.

DOI: doi:10.1111/imj.15589

Abstract

Patients with haematological malignancies, haemopoietic stem cell transplant recipients and patients requiring admission to intensive care settings are at high risk for invasive candidiasis (IC). Over the past decade, there has been increased reporting of non-albicans species and fluconazole resistance in Australia. These guidelines provide updated evidence-based recommendations for the diagnosis and management of IC in adult and paediatric haematology, oncology and intensive care settings. Optimal pharmacological and non-pharmacological management are discussed. Recent studies strengthen the recommendation for an echinocandin agent as first-line therapy for high-risk patients with IC. Mortality benefit has also been demonstrated for non-pharmacological management, including removal of central venous catheters, infectious diseases consultation and use of care bundles. Healthcare facilities managing immunocompromised patient populations should therefore adopt implementation strategies for these multimodal interventions.

Item Details

Item Type:Refereed Article
Keywords:invasive candidiasis, candidaemia, antifungaltherapy, consensus guidelines, diagnosis, prevention
Research Division:Biomedical and Clinical Sciences
Research Group:Cardiovascular medicine and haematology
Research Field:Respiratory diseases
Objective Division:Health
Objective Group:Clinical health
Objective Field:Clinical health not elsewhere classified
UTAS Author:Cooley, L (Dr Louise Cooley)
ID Code:152349
Year Published:2021
Web of Science® Times Cited:5
Deposited By:Medicine
Deposited On:2022-08-17
Last Modified:2022-09-21
Downloads:0

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