149943 - challenges incorporating digital health.pdf (121.64 kB)
Challenges of incorporating digital health technology outcomes in a clinical trial: experiences from PD STAT
journal contribution
posted on 2023-05-21, 07:27 authored by Day, JO, Smith, S, Noyce, AJ, Jane AltyJane Alty, Jeffery, A, Chapman, R, Carroll, CDigital health technologies (DHTs) have great potential for use as clinical trial outcomes; however, practical issues need to be addressed in order to maximise their benefit. We describe our experience of incorporating two DHTs as secondary/exploratory outcome measures in PD STAT, a randomised clinical trial of simvastatin in people with Parkinson’s disease. We found much higher rates of missing data in the DHTs than the traditional outcome measures, in particular due to technical and software difficulties. We discuss methods to address these obstacles in terms of protocol design, workforce training and data management.
History
Publication title
Journal of Parkinson's DiseaseVolume
12Issue
5Pagination
1605-1609ISSN
1877-7171Department/School
Wicking Dementia Research Education CentrePublisher
IOS PressPlace of publication
NetherlandsRights statement
© 2022 – The authors. Published by IOS Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non Commercial 4.0 International (CC BY-NC 4.0) License, (https://creativecommons.org/licenses/by-nc/4.0/)Repository Status
- Open