149661 - Host relatedness and landscape connectivity shape pathogen spread in the puma, a large secretive carnivore.pdf (1.77 MB)
Host relatedness and landscape connectivity shape pathogen spread in the puma, a large secretive carnivore
journal contribution
posted on 2023-05-21, 07:02 authored by Nicholas Fountain-JonesNicholas Fountain-Jones, Kraberger, S, Gagne, RB, Trumbo, DR, Salerno, PE, Funk, WC, Crooks, K, Biek, R, Alldredge, M, Logan, K, Baele, G, Dellicour, S, Ernest, HB, VandeWoude, S, Scott CarverScott Carver, Craft, MEUrban expansion can fundamentally alter wildlife movement and gene flow, but how urbanization alters pathogen spread is poorly understood. Here, we combine high resolution host and viral genomic data with landscape variables to examine the context of viral spread in puma (Puma concolor) from two contrasting regions: one bounded by the wildland urban interface (WUI) and one unbounded with minimal anthropogenic development (UB). We found landscape variables and host gene flow explained significant amounts of variation of feline immunodeficiency virus (FIV) spread in the WUI, but not in the unbounded region. The most important predictors of viral spread also differed; host spatial proximity, host relatedness, and mountain ranges played a role in FIV spread in the WUI, whereas roads might have facilitated viral spread in the unbounded region. Our research demonstrates how anthropogenic landscapes can alter pathogen spread, providing a more nuanced understanding of host-pathogen relationships to inform disease ecology in free-ranging species.
Funding
National Science Foundation
History
Publication title
Communications BiologyVolume
4Article number
12Number
12Pagination
1-9ISSN
2399-3642Department/School
School of Natural SciencesPublisher
Nature Publishing GroupPlace of publication
United KingdomRights statement
Copyright 2021 The Authors Licensed under Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/Repository Status
- Open