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Type 2 diabetes mellitus, interaction between left ventricle and large arteries


Boutouyrie, P and Climie, RE and Bruno, RM, Type 2 diabetes mellitus, interaction between left ventricle and large arteries, American Journal of Hypertension Article hpac007. ISSN 0895-7061 (2022) [Letter or Note in Journal]

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DOI: doi:10.1093/ajh/hpac007


A direct relationship between brachial pulse pressure (PP) and N-terminal prohormone of brain natriuretic peptide (NT-proBNP) has been demonstrated. NT-proBNP is a marker of cardiac overload and sensitive marker of heart failure. Brachial PP is an indirect marker of arterial stiffness and central pressure, whether arterial markers, mild elevation of BNP, or both directly contribute to excessive rate of events is unknown (question mark). Whether other mechanisms such as endothelial dysfunction or small artery disease contributes is unknown.

Item Details

Item Type:Letter or Note in Journal
Keywords:arterial physiology, blood pressure, vascular ageing, type 2 diabetes
Research Division:Biomedical and Clinical Sciences
Research Group:Cardiovascular medicine and haematology
Research Field:Cardiology (incl. cardiovascular diseases)
Objective Division:Health
Objective Group:Clinical health
Objective Field:Prevention of human diseases and conditions
UTAS Author:Climie, RE (Dr Rachel Climie)
ID Code:149621
Year Published:2022
Funding Support:National Health and Medical Research Council (2009005)
Web of Science® Times Cited:1
Deposited By:Menzies Institute for Medical Research
Deposited On:2022-04-05
Last Modified:2022-04-07

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