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Aortic pulsatility drives microvascular organ damage in essential hypertension: New evidence from choroidal thickness assessment
Citation
Bruno, RM and Climie, RE and Gallo, A, Aortic pulsatility drives microvascular organ damage in essential hypertension: New evidence from choroidal thickness assessment, Journal of Clinical Hypertension, 23, (5) pp. 1039-1040. ISSN 1524-6175 (2021) [Letter or Note in Journal]
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Abstract
In a healthy cardiovascular system, the compliant properties of the large arteries ensure that pulsations in pressure and flow generated by cyclic left ventricular contraction are dampened at the site of the ascending aorta into a continuous pressure (and flow) downstream at the site of arterioles. This allows for the delivery of a steady flow of blood during organ perfusion, and the microvasculature of target organs is protected from the damaging effects of pressure pulsatility.
Item Details
| Item Type: | Letter or Note in Journal |
|---|---|
| Keywords: | arterial physiology, blood pressure, vascular ageing |
| Research Division: | Biomedical and Clinical Sciences |
| Research Group: | Cardiovascular medicine and haematology |
| Research Field: | Cardiology (incl. cardiovascular diseases) |
| Objective Division: | Health |
| Objective Group: | Clinical health |
| Objective Field: | Prevention of human diseases and conditions |
| UTAS Author: | Climie, RE (Dr Rachel Climie) |
| ID Code: | 149618 |
| Year Published: | 2021 |
| Deposited By: | Menzies Institute for Medical Research |
| Deposited On: | 2022-04-05 |
| Last Modified: | 2022-04-07 |
| Downloads: | 0 |
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