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Aortic pulsatility drives microvascular organ damage in essential hypertension: New evidence from choroidal thickness assessment

Citation

Bruno, RM and Climie, RE and Gallo, A, Aortic pulsatility drives microvascular organ damage in essential hypertension: New evidence from choroidal thickness assessment, Journal of Clinical Hypertension, 23, (5) pp. 1039-1040. ISSN 1524-6175 (2021) [Letter or Note in Journal]


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DOI: doi:10.1111/jch.14195

Abstract

In a healthy cardiovascular system, the compliant properties of the large arteries ensure that pulsations in pressure and flow generated by cyclic left ventricular contraction are dampened at the site of the ascending aorta into a continuous pressure (and flow) downstream at the site of arterioles. This allows for the delivery of a steady flow of blood during organ perfusion, and the microvasculature of target organs is protected from the damaging effects of pressure pulsatility.

Item Details

Item Type:Letter or Note in Journal
Keywords:arterial physiology, blood pressure, vascular ageing
Research Division:Biomedical and Clinical Sciences
Research Group:Cardiovascular medicine and haematology
Research Field:Cardiology (incl. cardiovascular diseases)
Objective Division:Health
Objective Group:Clinical health
Objective Field:Prevention of human diseases and conditions
UTAS Author:Climie, RE (Dr Rachel Climie)
ID Code:149618
Year Published:2021
Deposited By:Menzies Institute for Medical Research
Deposited On:2022-04-05
Last Modified:2022-04-07
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