Sedentary behavior and mechanisms of cardiovascular disease-getting to the heart of the matter

Sedentary behavior has emerged as a distinct risk factor for disease and mortality. Recent meta-analyses have identified that only very high levels of moderate-to-vigorous physical activity (60–75 min/d) attenuate the associations of overall sitting time and all-cause mortality, whereas the risk of mortality associated with high television viewing time is evident at all levels of physical activity.