Towards an eco-phylogenetic framework for infectious disease ecology
Fountain-Jones, NM and Pearse, WD and Escobar, LE and Alba-Casals, A and Carver, S and Davies, TJ and Kraberger, S and Papes, M and Vandergrift, K and Worsley-Tonks, K and Craft, ME, Towards an eco-phylogenetic framework for infectious disease ecology, Biological Reviews, 93, (2) pp. 950-970. ISSN 1464-7931 (2017) [Refereed Article]
Identifying patterns and drivers of infectious disease dynamics across multiple scales is a fundamental challenge for modern science. There is growing awareness that it is necessary to incorporate multi-host and/or multi-parasite interactions to understand and predict current and future disease threats better, and new tools are needed to help address this task. Eco-phylogenetics (phylogenetic community ecology) provides one avenue for exploring multi-host multi-parasite systems, yet the incorporation of eco-phylogenetic concepts and methods into studies of host pathogen dynamics has lagged behind. Eco-phylogenetics is a transformative approach that uses evolutionary history to infer present-day dynamics. Here, we present an eco-phylogenetic framework to reveal insights into parasite communities and infectious disease dynamics across spatial and temporal scales. We illustrate how eco-phylogenetic methods can help untangle the mechanisms of host–parasite dynamics from individual (e.g. co-infection) to landscape scales (e.g. parasite/host community structure). An improved ecological understanding of multi-host and multi-pathogen dynamics across scales will increase our ability to predict disease threats.