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Sensory stimulation for apnoea mitigation in preterm infants


Lim, KL and Cramer, SJE and te Pas, AB and Gale, TJ and Dargaville, PA, Sensory stimulation for apnoea mitigation in preterm infants, Pediatric Research pp. 1-10. ISSN 0031-3998 (2021) [Refereed Article]

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Copyright The Author(s), under exclusive licence to the International Pediatric Research Foundation, Inc

DOI: doi:10.1038/s41390-021-01828-5


Apnoea, a pause in respiration, is ubiquitous in preterm infants and are often associated with physiological instability, which may lead to longer-term adverse neurodevelopmental consequences. Despite current therapies aimed at reducing the apnoea burden, preterm infants continue to exhibit apnoeic events throughout their hospital admission. Bedside staff are frequently required to manually intervene with different forms of stimuli, with the aim of re-establishing respiratory cadence and minimizing the physiological impact of each apnoeic event. Such a reactive approach makes apnoea and its associated adverse consequences inevitable and places a heavy reliance on human intervention. Different approaches to improving apnoea management in preterm infants have been investigated, including the use of various sensory stimuli. Despite studies reporting sensory stimuli of various forms to have potential in reducing apnoea frequency, non-invasive intermittent positive pressure ventilation is the only automated stimulus currently used in the clinical setting for infants with persistent apnoeic events. We find that the development of automated closed-looped sensory stimulation systems for apnoea mitigation in preterm infants receiving non-invasive respiratory support is warranted, including the possibility of stimulation being applied preventatively, and in a multi-modal form.

Item Details

Item Type:Refereed Article
Keywords:apnoea, preterm infant, mitigation, stimulus
Research Division:Engineering
Research Group:Biomedical engineering
Research Field:Medical devices
Objective Division:Health
Objective Group:Clinical health
Objective Field:Treatment of human diseases and conditions
UTAS Author:Lim, KL (Miss Kai Lim)
UTAS Author:Gale, TJ (Dr Timothy Gale)
UTAS Author:Dargaville, PA (Professor Peter Dargaville)
ID Code:149235
Year Published:2021
Deposited By:Engineering
Deposited On:2022-03-18
Last Modified:2022-08-25
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