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Synthesis of pyrrolidine- and γ-lactam-containing natural products and related compounds from pyrrole scaffolds
Citation
Olivier, WJ and Smith, JA and Bissember, AC, Synthesis of pyrrolidine- and γ-lactam-containing natural products and related compounds from pyrrole scaffolds, Chemical Record, 22, (3) Article e202100277. ISSN 1527-8999 (2021) [Refereed Article]
Copyright Statement
© 2021 The Chemical Society of Japan & Wiley-VCH GmbH
DOI: doi:10.1002/tcr.202100277
Abstract
Polycyclic alkaloid natural products featuring pyrrolidine and pyrrolidinone motifs remain enduring targets of total synthesis endeavors. Pyrrole and its derivatives have been exploited to access many such frameworks, including alkaloids belonging to the Aspidosperma, Stemona, and batzelladine families. In this article, a selection of exemplars that highlight the utility of pyrrole-based approaches to facilitate total syntheses of pyrrolidine- and pyrrolidinone-containing alkaloids and related molecules are showcased.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Keywords: | pyrrole, pyrrolidine, alkaloids, natural products, total synthesis |
| Research Division: | Chemical Sciences |
| Research Group: | Organic chemistry |
| Research Field: | Organic chemical synthesis |
| Objective Division: | Expanding Knowledge |
| Objective Group: | Expanding knowledge |
| Objective Field: | Expanding knowledge in the chemical sciences |
| UTAS Author: | Olivier, WJ (Mr Wesley Olivier) |
| UTAS Author: | Smith, JA (Associate Professor Jason Smith) |
| UTAS Author: | Bissember, AC (Associate Professor Alex Bissember) |
| ID Code: | 149112 |
| Year Published: | 2021 |
| Funding Support: | Australian Research Council (FT200100049) |
| Deposited By: | Chemistry |
| Deposited On: | 2022-03-10 |
| Last Modified: | 2022-04-07 |
| Downloads: | 0 |
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