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Synthesis of pyrrolidine- and γ-lactam-containing natural products and related compounds from pyrrole scaffolds

Citation

Olivier, WJ and Smith, JA and Bissember, AC, Synthesis of pyrrolidine- and γ-lactam-containing natural products and related compounds from pyrrole scaffolds, Chemical Record, 22, (3) Article e202100277. ISSN 1527-8999 (2021) [Refereed Article]

Copyright Statement

2021 The Chemical Society of Japan & Wiley-VCH GmbH

DOI: doi:10.1002/tcr.202100277

Abstract

Polycyclic alkaloid natural products featuring pyrrolidine and pyrrolidinone motifs remain enduring targets of total synthesis endeavors. Pyrrole and its derivatives have been exploited to access many such frameworks, including alkaloids belonging to the Aspidosperma, Stemona, and batzelladine families. In this article, a selection of exemplars that highlight the utility of pyrrole-based approaches to facilitate total syntheses of pyrrolidine- and pyrrolidinone-containing alkaloids and related molecules are showcased.

Item Details

Item Type:Refereed Article
Keywords:pyrrole, pyrrolidine, alkaloids, natural products, total synthesis
Research Division:Chemical Sciences
Research Group:Organic chemistry
Research Field:Organic chemical synthesis
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the chemical sciences
UTAS Author:Olivier, WJ (Mr Wesley Olivier)
UTAS Author:Smith, JA (Associate Professor Jason Smith)
UTAS Author:Bissember, AC (Associate Professor Alex Bissember)
ID Code:149112
Year Published:2021
Funding Support:Australian Research Council (FT200100049)
Deposited By:Chemistry
Deposited On:2022-03-10
Last Modified:2022-04-07
Downloads:0

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