148985 - Urban-rural prostate cancer disparities in a regional state.pdf (864.08 kB)
Urban–rural prostate cancer disparities in a regional state of Australia
journal contribution
posted on 2023-05-21, 06:01 authored by Georgea FoleyGeorgea Foley, Christopher BlizzardChristopher Blizzard, Stokes, B, Skala, M, Redwig, F, Joanne DickinsonJoanne Dickinson, Liesel FitzgeraldLiesel FitzgeraldMen living in regional and remote areas experience disparities in prostate cancer (PrCa) diagnosis, clinical characteristics and treatment modalities. We sought to determine whether such disparities exist in PrCa patients from Tasmania; a regional state of Australia with the second-highest rate of diagnosis and where over a third of residents live in outer regional and remote areas. Our study included clinicopathological data from 1526 patients enrolled in the Prostate Cancer Outcomes Registry-Tasmania. Regression analyses were undertaken to determine whether demographic, clinical and treatment variables differed between inner regional and outer regional/remote patients. Men from outer regional/remote areas were significantly more likely to reside in lower socio-economic areas, be diagnosed at a later age and with more clinically aggressive features. However, in contrast to previous studies, there were no overall differences in diagnostic or treatment method, although men from outer regional/remote areas took longer to commence active treatment and travelled further to do so. This study is the first to investigate PrCa disparities in a wholly regional Australian state and highlights the need to develop systematic interventions at the patient and healthcare level to improve outcomes in outer regional and remote populations in Australia and across the globe.
History
Publication title
Scientific ReportsVolume
12Article number
3022Number
3022Pagination
1-8ISSN
2045-2322Department/School
Menzies Institute for Medical ResearchPublisher
Nature Publishing GroupPlace of publication
United KingdomRights statement
© The Author(s) 2022. This article is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. http://creat ivecommons.org/licenses/by/4.0/.Repository Status
- Open