148687 - Elimination of aliasing - Author version.pdf (1.03 MB)
Elimination of aliasing in LA-ICP-MS by alignment of laser and mass spectrometer†
journal contribution
posted on 2023-05-21, 05:30 authored by Norris, CA, Leonid Danyushevsky, Paul Olin, West, NRInsufficient sampling of periodic signals results in an unwanted phenomenon known as aliasing. When measuring by LA-ICP-MS it is widely observed that aliasing between laser pulse rates and sampling by sequential ICP-MS instruments creates erroneous variations in the measured element concentrations in the sample. Smoothing the sample flow to the ICP-MS can largely eliminate this variation but reduces spatial resolution of the time-resolved signal and is thus detrimental for imaging with the increasingly popular fast response sample cells. We have developed a fire control circuit that fires the laser in alignment with the measurement cycle of the mass spectrometer to lessen or eliminate aliasing. We describe the device and show that with a conventional quadrupole ICP-MS the technique is able to maintain measurement precision when the extent of mixing between individual laser pulses is reduced by an order of magnitude.
History
Publication title
Journal of Analytical Atomic SpectrometryVolume
36Issue
4Pagination
733-739ISSN
1364-5544Department/School
School of Natural SciencesPublisher
Royal Society of ChemistryPlace of publication
United KingdomRights statement
© The Royal Society of Chemistry 2021Repository Status
- Open