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Chronic pain alters spatiotemporal activation patterns of forearm muscle synergies during the development of grip force
Citation
Manickaraj, N and Bisset, L and Devanaboyina, VSPT and Kavanagh, JJ, Chronic pain alters spatiotemporal activation patterns of forearm muscle synergies during the development of grip force, Journal of Neurophysiology, 118 pp. 2132-2141. ISSN 0022-3077 (2017) [Refereed Article]
Copyright Statement
Copyright © 2017 the American Physiological Society
DOI: doi:10.1152/jn.00210.2017
Abstract
It is largely unknown how the CNS regulates
multiple muscle systems in the presence of pain. This study used
muscle synergy analysis to investigate multiple forearm muscles in
individuals with chronic elbow pain during the development of grip
force. Eleven individuals with chronic elbow pain and 11 healthy
age-matched control subjects developed grip force to 15% and 30% of
maximum voluntary contraction (MVC). Surface electromyography
was obtained from six forearm muscles during force development
before nonnegative matrix factorization was performed. The relationship
between muscle synergies and standard clinical tests of elbow
pain were examined by linear regression. During grip force development
to 15% MVC the pain group had a lower number of forearm
muscle synergies, increased similarity in spatial activation patterns,
increased cocontraction of forearm flexors, and a greater magnitude of
muscle weightings across the forearm when performing the task.
During the 30% MVC grip the numbers of muscle synergies were the
same for both groups; however, the pain group had lower activation
and reduced variability in the timing of peak activation. The timing of
peak activation was delayed in the pain group regardless of the task,
and performing the grip in different wrist postures did not affect
muscle synergy characteristics in either group. Although localized
pain causes direct dysfunction of an affected muscle, this study
provides evidence that the timing and amplitude of agonist and
antagonist muscle activity are also affected with chronic pain.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Keywords: | pain, motor control, muscle synergy, tennis elbow |
| Research Division: | Health Sciences |
| Research Group: | Sports science and exercise |
| Research Field: | Motor control |
| Objective Division: | Health |
| Objective Group: | Clinical health |
| Objective Field: | Diagnosis of human diseases and conditions |
| UTAS Author: | Manickaraj, N (Dr Nagarajan Manickaraj) |
| ID Code: | 148370 |
| Year Published: | 2017 |
| Web of Science® Times Cited: | 12 |
| Deposited By: | Health Sciences |
| Deposited On: | 2022-01-04 |
| Last Modified: | 2022-08-23 |
| Downloads: | 0 |
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