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An overview of vaccine development for COVID-19

Citation

Shahcheraghi, SH and Ayatollahi, J and Aljabali, AAA and Shastri, M and Shukla, SD and Chellappan, DK and Jha, NK and Anand, K and Katari, NK and Mehta, M and Satija, S and Dureja, H and Mishra, V and Almutary, AG and Alnuqaydan, AM and Charbe, N and Prasher, P and Gupta, G and Dua, K and Lotfi, M and Bakshi, HA and Tambuwala, MM, An overview of vaccine development for COVID-19, Therapeutic Delivery, 12, (3) pp. 235-244. ISSN 2041-5990 (2021) [Refereed Article]


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DOI: doi:10.4155/tde-2020-0129

Abstract

The COVID-19 pandemic continues to endanger world health and the economy. The causative SARS-CoV-2 coronavirus has a unique replication system. The end point of the COVID-19 pandemic is either herd immunity or widespread availability of an effective vaccine. Multiple candidate vaccines - peptide, virus-like particle, viral vectors (replicating and nonreplicating), nucleic acids (DNA or RNA), live attenuated virus, recombinant designed proteins and inactivated virus - are presently under various stages of expansion, and a small number of vaccine candidates have progressed into clinical phases. At the time of writing, three major pharmaceutical companies, namely Pfizer and Moderna, have their vaccines under mass production and administered to the public. This review aims to investigate the most critical vaccines developed for COVID-19 to date.

Item Details

Item Type:Refereed Article
Keywords:COVID-19, COVID-19 vaccines, SARS-CoV-2
Research Division:Biomedical and Clinical Sciences
Research Group:Pharmacology and pharmaceutical sciences
Research Field:Clinical pharmacology and therapeutics
Objective Division:Health
Objective Group:Clinical health
Objective Field:Prevention of human diseases and conditions
UTAS Author:Shastri, M (Mr Madhur Shastri)
ID Code:147458
Year Published:2021
Web of Science® Times Cited:7
Deposited By:Pharmacy
Deposited On:2021-11-02
Last Modified:2021-11-02
Downloads:0

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