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Influence of tDCS over right inferior frontal gyrus and pre-supplementary motor area on perceptual decision-making and response inhibition: A healthy ageing perspective

Citation

Fujiyama, H and Tan, J and Puri, R and Hinder, MR, Influence of tDCS over right inferior frontal gyrus and pre-supplementary motor area on perceptual decision-making and response inhibition: A healthy ageing perspective, Neurobiology of Aging, 109 pp. 11-21. ISSN 0197-4580 (2022) [Refereed Article]

Copyright Statement

2021 Elsevier Inc.

DOI: doi:10.1016/j.neurobiolaging.2021.09.014

Abstract

A wide body of literature suggests that transcranial direct current stimulation (tDCS) administered over the prefrontal cortex can improve executive function including decision-making and inhibitory control in healthy young adults. However, the effects of tDCS in older adults are largely unknown. Here, using a double-blind, sham-controlled approach, changes in a combined perceptual decision-making and inhibitory control task were assessed before and after the application of tDCS (1 mA, 20 minute) targeting the right inferior frontal gyrus (rIFG) or pre-supplementary motor area (preSMA) in 42 young (1834 years) and 41 older (6080 years) healthy adults. Compared to sham stimulation, anodal tDCS over the preSMA improved decision-making speed for both age groups. Furthermore, the inhibitory control performance of older and younger adults was improved by preSMA and rIFG stimulation, respectively. This study provides evidence that tDCS can improve both perceptual decision-making and inhibitory control in healthy older adults, with the causal role of the preSMA and rIFG regions in cognitive control appearing to vary as a function of healthy ageing.

Item Details

Item Type:Refereed Article
Keywords:inhibitory control, ageing, cognitive control
Research Division:Psychology
Research Group:Biological psychology
Research Field:Cognitive neuroscience
Objective Division:Health
Objective Group:Specific population health (excl. Indigenous health)
Objective Field:Health related to ageing
UTAS Author:Puri, R (Mr Rohan Puri)
UTAS Author:Hinder, MR (Associate Professor Mark Hinder)
ID Code:147431
Year Published:2022
Funding Support:Australian Research Council (DP200101696)
Deposited By:Psychology
Deposited On:2021-11-01
Last Modified:2021-12-01
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