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Draft genome sequence of a nontypeable Haemophilus influenzae strain used in the study of human respiratory infection


Kc, R and O'Toole, RF, Draft genome sequence of a nontypeable Haemophilus influenzae strain used in the study of human respiratory infection, BMC Research Notes, 14, (1) pp. 1-4. ISSN 1756-0500 (2021) [Refereed Article]

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The Author(s) 2021. This article is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) License, ( which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.

DOI: doi:10.1186/s13104-021-05528-5


Objectives: Nontypeable Haemophilus influenzae (NTHi) is an important human respiratory bacterium that can cause a range of diseases including sinusitis, otitis media, conjunctivitis, pneumonia as well as acute exacerbations of chronic obstructive pulmonary disease (COPD). A number of studies have used NTHi clinical isolate RHH-3 as a laboratory strain for experimentation examining the effect of cigarette smoke and more recently, biomass smoke, on the susceptibility and response of cells lining the respiratory tract to infection. Therefore, definition of the genome content of RHH-3 is required to fully elucidate human-NTHi interactions associated with initial infection and subsequent development of respiratory disease.

Data description: Here, we present the draft genome sequence of NTHi RHH-3 collected from the sputum of a patient at the Royal Hobart Hospital, Tasmania, Australia. The assembled genome size was 1,839,376 bp consisting of 61 contigs (> 500 bp), with a G+C content of 38.1%. This draft genome data can be accessed at DDBJ/ENA/GenBank under the accession number JADPRR000000000.

Item Details

Item Type:Refereed Article
Keywords:chronic obstructive pulmonary disease, nontypeable Haemophilus influenzae, whole genome sequence
Research Division:Biomedical and Clinical Sciences
Research Group:Clinical sciences
Research Field:Infectious diseases
Objective Division:Health
Objective Group:Clinical health
Objective Field:Diagnosis of human diseases and conditions
UTAS Author:Kc, R (Dr Rajendra KC)
UTAS Author:O'Toole, RF (Dr Ronan O'Toole)
ID Code:147345
Year Published:2021
Deposited By:Menzies Institute for Medical Research
Deposited On:2021-10-27
Last Modified:2021-11-19
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