eCite Digital Repository
Emerging advances of nanotechnology in drug and vaccine delivery against viral associated respiratory infectious diseases (VARID)
Citation
Seyfoori, A and Barough, MS and Mokarram, P and Ahmadi, M and Mehrbod, P and Sheidary, A and Madrakian, T and Kiumarsi, M and Walsh, T and McAlinden, KD and Ghosh, CC and Sharma, P and Zeki, AA and Ghavami, S and Akbari, M, Emerging advances of nanotechnology in drug and vaccine delivery against viral associated respiratory infectious diseases (VARID), International Journal of Molecular Sciences, 22, (13) Article 6937. ISSN 1661-6596 (2021) [Refereed Article]
 | PDF 3Mb |
Copyright Statement
Copyright 2021 The Authors. Licensed under Creative Commons Attribution 4.0 International (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/
Abstract
Viral-associated respiratory infectious diseases are one of the most prominent subsets of respiratory failures, known as viral respiratory infections (VRI). VRIs are proceeded by an infection caused by viruses infecting the respiratory system. For the past 100 years, viral associated respiratory epidemics have been the most common cause of infectious disease worldwide. Due to several drawbacks of the current anti-viral treatments, such as drug resistance generation and non-targeting of viral proteins, the development of novel nanotherapeutic or nano-vaccine strategies can be considered essential. Due to their specific physical and biological properties, nanoparticles hold promising opportunities for both anti-viral treatments and vaccines against viral infections. Besides the specific physiological properties of the respiratory system, there is a significant demand for utilizing nano-designs in the production of vaccines or antiviral agents for airway-localized administration. SARS-CoV-2, as an immediate example of respiratory viruses, is an enveloped, positive-sense, single-stranded RNA virus belonging to the coronaviridae family. COVID-19 can lead to acute respiratory distress syndrome, similarly to other members of the coronaviridae. Hence, reviewing the current and past emerging nanotechnology-based medications on similar respiratory viral diseases can identify pathways towards generating novel SARS-CoV-2 nanotherapeutics and/or nano-vaccines.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Keywords: | COVID-19, SARS-CoV-2, nano-vaccine, nanomedicine, respiratory disease, viral infection |
| Research Division: | Biomedical and Clinical Sciences |
| Research Group: | Cardiovascular medicine and haematology |
| Research Field: | Respiratory diseases |
| Objective Division: | Health |
| Objective Group: | Clinical health |
| Objective Field: | Treatment of human diseases and conditions |
| UTAS Author: | McAlinden, KD (Mr Kielan McAlinden) |
| ID Code: | 146626 |
| Year Published: | 2021 |
| Web of Science® Times Cited: | 7 |
| Deposited By: | Health Sciences |
| Deposited On: | 2021-09-17 |
| Last Modified: | 2022-12-06 |
| Downloads: | 13 View Download Statistics |
Repository Staff Only: item control page