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Small-footprint, field-deployable LC/MS system for on-site analysis of per- and polyfluoroalkyl substances in soil


Hemida, MH and Ghiasvand, A and Gupta, V and Coates, LJ and Gooley, AA and Wirth, H and Haddad, PR, Small-footprint, field-deployable LC/MS system for on-site analysis of per- and polyfluoroalkyl substances in soil, Analytical Chemistry, 93, (35) pp. 12032-12040. ISSN 0003-2700 (2021) [Refereed Article]

Copyright Statement

Copyright 2021 American Chemical Society

DOI: doi:10.1021/acs.analchem.1c02193


Per- and polyfluoroalkyl substances (PFASs) are emerging environmental pollutants of global concern. For rapid field site evaluation, there are very few sensitive, field-deployable analytical techniques. In this work, a portable lightweight capillary liquid chromatography (capLC) system was coupled with a small footprint portable mass spectrometer and configured for field-based applications. Further, an at-site ultrasound-assisted extraction (pUAE) methodology was developed and applied with a portable capLC/mass spectrometry (MS) system for on-site analysis of PFASs in real soil samples. The influential variables on the integration of capLC with MS and on the resolution and signal intensity of the capLC/MS setup were investigated. The important parameters affecting the efficiency of the pUAE method were also studied and optimized using the response surface methodology based on a central composite design. The mean recovery for 11 PFASs ranged between 70 and 110%, with relative standard deviations ranging from 3 to 12%. In-field method sensitivity for 12 PFASs ranged from 0.6 to 0.1 ng/g, with wide dynamic ranges (1–600 ng/g) and excellent linearities (R2 > 0.991). The in-field portable system was benchmarked against a commercial lab-based LC–tandem MS (MS/MS) system for the analysis of PFASs in real soil samples, with the results showing good agreement. When deployed to a field site, 12 PFASs were detected and identified in real soil samples at concentrations ranging from 8.1 ng/g (for perfluorooctanesulfonic acid) to 2935.0 ng/g (perfluorohexanesulfonic acid).

Item Details

Item Type:Refereed Article
Keywords:field-deployable LC-MS, on-site analysis, per- and polyfluoroalkyl substances, soil
Research Division:Chemical Sciences
Research Group:Analytical chemistry
Research Field:Separation science
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the chemical sciences
UTAS Author:Hemida, MH (Mr Mohamed Hemida)
UTAS Author:Ghiasvand, A (Professor Alireza Ghiasvand)
UTAS Author:Gupta, V (Dr Vipul Gupta)
UTAS Author:Coates, LJ (Mr Lewellwyn Coates)
UTAS Author:Gooley, AA (Dr Andrew Gooley)
UTAS Author:Wirth, H (Dr Hans-Jurgen Wirth)
UTAS Author:Haddad, PR (Professor Paul Haddad)
ID Code:146510
Year Published:2021
Web of Science® Times Cited:5
Deposited By:Chemistry
Deposited On:2021-09-09
Last Modified:2022-08-23

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