Jose, M and Raj, R and Jose, K and Kitsos, AR and Saunder, THC and McKercher, C and Radford, J, Island medicine: using data linkage to establish the kidney health of the population of Tasmania, Australia, International Journal of Population Data Science, 6, (1) pp. 1-11. ISSN 2399-4908 (2021) [Refereed Article]
Objective: To report (using linked laboratory data) the incidence, prevalence and geographic variation of chronic kidney disease (CKD) across the whole island population of Tasmania, Australia.
Methods: A retrospective cohort study (the Tasmanian Chronic Kidney Disease study (CKD.TASlink)) using linked data from five health and two pathology datasets from the island state of Tasmania, Australia between 1/1/2004 and 31/12/2017. We used data on 460,737 Tasmanian adults (aged 18 years and older, representing 86.8% of the state's population) who had a serum creatinine measured during the study period. We defined CKD as per Kidney Disease Outcomes Quality Initiative, requiring two measures of estimated glomerular filtration rate (eGFR) <60 mL/min/1.73m2, at least three months apart. Kidney replacement therapy (KRT) included dialysis or kidney transplantation.
Results: We identified 56,438 Tasmanians with CKD during the study period, equating to an age-standardised annual incidence of 1.0% and a prevalence of 6.5%. These figures were higher in women, older Tasmanians and people living in the North-West region of Tasmania. Testing for urinary albumin:creatinine ratio is increasing, with 28.5% of women and 30.8% of men with stage 3 CKD having both an eGFR and uACR in 2017. Use of KRT was consistently seen in >65% of Tasmanians with eGFR <15 mL/min/1.73m2.
Conclusion: There is geographic and gender variation in the incidence and prevalence of CKD, but it is reassuring to see that the majority of people with end-stage kidney failure are actually receiving treatment with dialysis or transplantation.
|Item Type:||Refereed Article|
|Keywords:||chronic kidney disease, dialysis, epidemiology, transplantation, Tasmania, data linkage,|
|Research Division:||Biomedical and Clinical Sciences|
|Research Group:||Clinical sciences|
|Research Field:||Nephrology and urology|
|Objective Group:||Clinical health|
|Objective Field:||Diagnosis of human diseases and conditions|
|UTAS Author:||Jose, M (Professor Matthew Jose)|
|UTAS Author:||Raj, R (Dr Rajesh Raj)|
|UTAS Author:||Jose, K (Dr Kim Jose)|
|UTAS Author:||Kitsos, AR (Mr Alex Kitsos)|
|UTAS Author:||Saunder, THC (Mr Timothy Saunder)|
|UTAS Author:||McKercher, C (Dr Charlotte McKercher)|
|UTAS Author:||Radford, J (Associate Professor Jan Radford)|
|Deposited By:||Menzies Institute for Medical Research|
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