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Metabolic changes induced by purinergic signaling: Role in food intake


Caruso, V and Zuccarini, M and Di Iorio, P and Muhammad, I and Ronci, M, Metabolic changes induced by purinergic signaling: Role in food intake, Frontiers in Pharmacology pp. 1-7. ISSN 1663-9812 (2021) [Substantial Review]

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DOI: doi:10.3389/fphar.2021.655989


The purinergic signalling has a well-established role in the regulation of energy homeostasis, but there is growing evidence of its implication in the control of food intake. In this review, we provide an integrative view of the molecular mechanisms leading to changes in feeding behaviour within hypothalamic neurons following purinergic receptor activation. We also highlight the importance of purinergic signalling in metabolic homeostasis and the possibility of targeting its receptors for therapeutic purposes.

Item Details

Item Type:Substantial Review
Keywords:obesity, purinergic system, weight loss, hypothalamus
Research Division:Biomedical and Clinical Sciences
Research Group:Pharmacology and pharmaceutical sciences
Research Field:Pharmaceutical sciences
Objective Division:Health
Objective Group:Clinical health
Objective Field:Prevention of human diseases and conditions
UTAS Author:Caruso, V (Dr Vanni Caruso)
UTAS Author:Muhammad, I (Dr Muhammad Ishaq)
ID Code:146305
Year Published:2021
Web of Science® Times Cited:1
Deposited By:Pharmacy
Deposited On:2021-08-30
Last Modified:2021-08-31

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