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Metabolic changes induced by purinergic signaling: Role in food intake
Citation
Caruso, V and Zuccarini, M and Di Iorio, P and Muhammad, I and Ronci, M, Metabolic changes induced by purinergic signaling: Role in food intake, Frontiers in Pharmacology pp. 1-7. ISSN 1663-9812 (2021) [Substantial Review]
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DOI: doi:10.3389/fphar.2021.655989
Abstract
The purinergic signalling has a well-established role in the regulation of energy homeostasis, but there is growing evidence of its implication in the control of food intake. In this review, we provide an integrative view of the molecular mechanisms leading to changes in feeding behaviour within hypothalamic neurons following purinergic receptor activation. We also highlight the importance of purinergic signalling in metabolic homeostasis and the possibility of targeting its receptors for therapeutic purposes.
Item Details
| Item Type: | Substantial Review |
|---|---|
| Keywords: | obesity, purinergic system, weight loss, hypothalamus |
| Research Division: | Biomedical and Clinical Sciences |
| Research Group: | Pharmacology and pharmaceutical sciences |
| Research Field: | Pharmaceutical sciences |
| Objective Division: | Health |
| Objective Group: | Clinical health |
| Objective Field: | Prevention of human diseases and conditions |
| UTAS Author: | Caruso, V (Dr Vanni Caruso) |
| UTAS Author: | Muhammad, I (Dr Muhammad Ishaq) |
| ID Code: | 146305 |
| Year Published: | 2021 |
| Deposited By: | Pharmacy |
| Deposited On: | 2021-08-30 |
| Last Modified: | 2021-08-31 |
| Downloads: | 0 |
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