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Work productivity trajectories of Australians living with multiple sclerosis: A group-based modelling approach


Bessing, B and Hussain, MA and Claflin, SB and Chen, J and Blizzard, L and van Dijk, P and Kirk-Brown, A and Taylor, BVM and van der Mei, I, Work productivity trajectories of Australians living with multiple sclerosis: A group-based modelling approach, Multiple Sclerosis and Related Disorders, 54 Article online ahead of print. ISSN 2211-0348 (2021) [Refereed Article]

Copyright Statement

2021 Elsevier B.V.

DOI: doi:10.1016/j.msard.2021.103131


Background: Studies have documented reduced work capacity and work productivity loss in multiple sclerosis (MS). Little is known about the longitudinal trajectories of work productivity in MS.

Objectives: To examine trajectories of work productivity in people living with multiple sclerosis (PwMS) and the factors associated with the trajectories.

Methods: Study participants were employed participants of the Australian MS Longitudinal Study (AMSLS) followed from 2015 to 2019 with at least two repeated measures (n=2121). We used group-based trajectory modelling to identify unique work productivity trajectories in PwMS.

Results: We identified three distinct trajectories of work productivity: 'moderately reduced' (17.0% of participants) with a mean work productivity level of 47.6% in 2015 (slope -0.97% per year (p= 0.22)), 'mildly reduced' (46.7%) with a mean work productivity of 86.3% in 2015 (slope 0.70% per year (p=0.12)), and 'full' (36.3%) with a mean work productivity of 99.7% in 2015 (slope 0.29% per year (p= 0.30)). Higher education level, higher disability, and higher MS symptom severity are associated with increased probability of being in a worse work productivity trajectory.

Conclusion: We identified three distinct work productivity trajectories in PwMS which were stable over time and differentiated by their baseline level of work productivity.

Item Details

Item Type:Refereed Article
Keywords:absenteeism, fatigue, multiple sclerosis, presenteeism, symptoms, trajectories, work productivity
Research Division:Biomedical and Clinical Sciences
Research Group:Neurosciences
Research Field:Neurology and neuromuscular diseases
Objective Division:Health
Objective Group:Clinical health
Objective Field:Treatment of human diseases and conditions
UTAS Author:Bessing, B (Mr Barnabas Bessing)
UTAS Author:Hussain, MA (Dr Akhtar Hussain)
UTAS Author:Claflin, SB (Dr Suzi Claflin)
UTAS Author:Chen, J (Miss Jing Chen)
UTAS Author:Blizzard, L (Professor Leigh Blizzard)
UTAS Author:Taylor, BVM (Professor Bruce Taylor)
UTAS Author:van der Mei, I (Professor Ingrid van der Mei)
ID Code:146175
Year Published:2021
Web of Science® Times Cited:7
Deposited By:Menzies Institute for Medical Research
Deposited On:2021-08-24
Last Modified:2022-08-23

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