Bessing, B and Hussain, MA and Claflin, SB and Chen, J and Blizzard, L and van Dijk, P and Kirk-Brown, A and Taylor, BV and van der Mei, I, Work productivity trajectories of Australians living with multiple sclerosis: A group-based modelling approach, Multiple Sclerosis and Related Disorders, 54 Article online ahead of print. ISSN 2211-0348 (2021) [Refereed Article]
© 2021 Elsevier B.V.
Background: Studies have documented reduced work capacity and work productivity loss in multiple sclerosis (MS). Little is known about the longitudinal trajectories of work productivity in MS.
Objectives: To examine trajectories of work productivity in people living with multiple sclerosis (PwMS) and the factors associated with the trajectories.
Methods: Study participants were employed participants of the Australian MS Longitudinal Study (AMSLS) followed from 2015 to 2019 with at least two repeated measures (n=2121). We used group-based trajectory modelling to identify unique work productivity trajectories in PwMS.
Results: We identified three distinct trajectories of work productivity: 'moderately reduced' (17.0% of participants) with a mean work productivity level of 47.6% in 2015 (slope -0.97% per year (p= 0.22)), 'mildly reduced' (46.7%) with a mean work productivity of 86.3% in 2015 (slope 0.70% per year (p=0.12)), and 'full' (36.3%) with a mean work productivity of 99.7% in 2015 (slope 0.29% per year (p= 0.30)). Higher education level, higher disability, and higher MS symptom severity are associated with increased probability of being in a worse work productivity trajectory.
Conclusion: We identified three distinct work productivity trajectories in PwMS which were stable over time and differentiated by their baseline level of work productivity.
|Item Type:||Refereed Article|
|Keywords:||absenteeism, fatigue, multiple sclerosis, presenteeism, symptoms, trajectories, work productivity|
|Research Division:||Biomedical and Clinical Sciences|
|Research Field:||Neurology and neuromuscular diseases|
|Objective Group:||Clinical health|
|Objective Field:||Treatment of human diseases and conditions|
|UTAS Author:||Bessing, B (Mr Barnabas Bessing)|
|UTAS Author:||Hussain, MA (Dr Akhtar Hussain)|
|UTAS Author:||Claflin, SB (Dr Suzi Claflin)|
|UTAS Author:||Chen, J (Miss Jing Chen)|
|UTAS Author:||Blizzard, L (Professor Leigh Blizzard)|
|UTAS Author:||Taylor, BV (Professor Bruce Taylor)|
|UTAS Author:||van der Mei, I (Professor Ingrid van der Mei)|
|Deposited By:||Menzies Institute for Medical Research|
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