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Appropriateness and determinants of proper administration technique of ocular hypotensive agents among glaucoma patients in Menelik II Referral Hospital, Ethiopia


Atey, T and Giorgis, AT and Shibeshi, W, Appropriateness and determinants of proper administration technique of ocular hypotensive agents among glaucoma patients in Menelik II Referral Hospital, Ethiopia, Journal of Clinical & Experimental Ophtalmology, 7, (3) pp. 1-8. ISSN 2155-9570 (2016) [Refereed Article]


Copyright Statement

Copyright: 2016 Mehari T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

DOI: doi:10.4172/2155-9570.1000554


Introduction: Appropriate administration of ocular hypotensive agents is required to lower an elevated intraocular pressure, prevent progressive damage of optic nerve head and visual field loss.

Objective: The main purpose of the study was to assess appropriateness of administration technique of ocular hypotensive agents and to identify factors associated with the proper technique.

Methods: A hospital-based cross-sectional study was conducted among 359 study participants in Menelik II Referral Hospital from June, 2015 to July 3, 2015. Eligible patients were interviewed and their medical charts were reviewed using a pretested structured questionnaire. Administration technique was assessed using nine-items of World Health Organization guide and associated factors were identified using multivariate binary logistic regression analysis. The association was declared significant at p<0.05.

Results: The rate of appropriate administration technique was 17.3%. Patients with advanced glaucoma (AOR=3.46, 95% CI: 1.09-10.97, p<0.035) and who had a more frequent follow-up (AOR=5.94, 95% CI: 1.19-29.62, p<0.030) were significantly associated with the appropriate administration technique. Patients with primary angle closure glaucoma (AOR=0.0, 95% CI: 0.00-0.25, p<0.022) and open angle glaucoma (AOR=0.0, 95% CI: 0.00-0.36, p<0.027), who immediately administered a second drop (AOR=0.0, 95% CI: 0.01-0.58, p<0.027), who experienced a side effect (AOR=0.13, 95% CI: 0.02-0.92, p<0.041) and who had low vision (AOR=0.0, 95% CI: 0.00-0.37, p<0.024) were inversely associated with the technique.

Conclusion: The administration technique was poor and sub-optimal according to the World Health Organization guide. Adoption and implementation of the guide are required to improve the instillation proficiency and optimize the glaucoma therapy.

Item Details

Item Type:Refereed Article
Keywords:pharmacy, clinical pharmacy, pharmacy practice
Research Division:Biomedical and Clinical Sciences
Research Group:Pharmacology and pharmaceutical sciences
Research Field:Clinical pharmacy and pharmacy practice
Objective Division:Manufacturing
Objective Group:Human pharmaceutical products
Objective Field:Human pharmaceutical treatments
UTAS Author:Atey, T (Mr Tesfay Mehari Atey)
ID Code:146029
Year Published:2016
Deposited By:Pharmacy
Deposited On:2021-08-18
Last Modified:2021-11-10
Downloads:6 View Download Statistics

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