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Time to death and risk factors among tuberculosis patients in Northern Ethiopia

Citation

Asgedom, SW and Tesfaye, D and Nirayo, YL and Atey, TM, Time to death and risk factors among tuberculosis patients in Northern Ethiopia, BMC Research Notes, 11 pp. 1-6. ISSN 1756-0500 (2018) [Refereed Article]


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Copyright Statement

© The Author(s) 2018. Open Access This article is licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) License, (https://creativecommons.org/licenses/by/4.0/) which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.

DOI: doi:10.1186/s13104-018-3806-7

Abstract

Objective: The main objective of this study was to assess time to death and associated risk factors among tuberculosis (TB) patients.

Results: A total of 769 TB patients were studied and of those, 87 (11.3%) patients died. All of the deaths occurred within 7 months of anti-tuberculosis therapy. Extra-pulmonary TB (AHR = 17.376, 95% CI; 3.88–77.86, p < 0.001) as compared to pulmonary TB and cotrimoxazole prophylaxis therapy (CPT) (AHR = 0.15, 95% CI; 0.03–0.74, p = 0.02) were found to be the predictors of mortality. We noticed higher rates of mortality. Extra-pulmonary TB patients have high risk and TB-HIV co-infected patients who received CPT have low risk of death. Improving early diagnosis of extra-pulmonary TB and early CPT initiation of TB-HIV co-infected patients could minimize patient’s mortality.

Item Details

Item Type:Refereed Article
Keywords:time to death, tuberculosis, risk factors, Ethiopia
Research Division:Biomedical and Clinical Sciences
Research Group:Pharmacology and pharmaceutical sciences
Research Field:Clinical pharmacy and pharmacy practice
Objective Division:Manufacturing
Objective Group:Human pharmaceutical products
Objective Field:Human pharmaceutical treatments
UTAS Author:Atey, TM (Mr Tesfay Atey)
ID Code:145997
Year Published:2018
Deposited By:Pharmacy
Deposited On:2021-08-17
Last Modified:2021-09-08
Downloads:9 View Download Statistics

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