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A patient with neuro-Behçet's disease is successfully treated with etanercept: Further evidence for the value of TNFα blockade
Citation
Alty, JE and Monaghan, TM and Bamford, JM, A patient with neuro-Behcet's disease is successfully treated with etanercept: Further evidence for the value of TNFα blockade, Clinical Neurology and Neurosurgery, 109, (3) pp. 279-281. ISSN 0303-8467 (2007) [Contribution to Refereed Journal]
 | Open XML Document (https://doi.org/10.1016/j.clineuro.2006.11.002) Pending copyright assessment - Request a copy 15Kb |
DOI: doi:10.1016/j.clineuro.2006.11.002
Abstract
Behcet's disease is a chronic relapsing multisystem vasculitis with 49% of cases involving the CNS. Recently there have been two reports of neuro-Behcet's disease (NB) successfully treated with the tumour necrosis factor α (TNFα) monoclonal antibody infliximab. We describe a patient with longstanding NB who was poorly responsive to azathioprine, cyclosporin, thalidomide and methotrexate. She showed a remarkable response when treated with the recombinant human TNFα receptor protein, etanercept. To the best of our knowledge this is the first report of NB successfully treated with etanercept.
Item Details
| Item Type: | Contribution to Refereed Journal |
|---|---|
| Keywords: | neurology, diagnosis, treatment, inflammatory |
| Research Division: | Biomedical and Clinical Sciences |
| Research Group: | Neurosciences |
| Research Field: | Central nervous system |
| Objective Division: | Health |
| Objective Group: | Clinical health |
| Objective Field: | Treatment of human diseases and conditions |
| UTAS Author: | Alty, JE (Associate Professor Jane Alty) |
| ID Code: | 145415 |
| Year Published: | 2007 |
| Web of Science® Times Cited: | 36 |
| Deposited By: | Wicking Dementia Research and Education Centre |
| Deposited On: | 2021-07-21 |
| Last Modified: | 2021-08-06 |
| Downloads: | 0 |
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