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A patient with neuro-Behçet's disease is successfully treated with etanercept: Further evidence for the value of TNFα blockade


Alty, JE and Monaghan, TM and Bamford, JM, A patient with neuro-Behcet's disease is successfully treated with etanercept: Further evidence for the value of TNFα blockade, Clinical Neurology and Neurosurgery, 109, (3) pp. 279-281. ISSN 0303-8467 (2007) [Contribution to Refereed Journal]

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DOI: doi:10.1016/j.clineuro.2006.11.002


Behcet's disease is a chronic relapsing multisystem vasculitis with 49% of cases involving the CNS. Recently there have been two reports of neuro-Behcet's disease (NB) successfully treated with the tumour necrosis factor α (TNFα) monoclonal antibody infliximab. We describe a patient with longstanding NB who was poorly responsive to azathioprine, cyclosporin, thalidomide and methotrexate. She showed a remarkable response when treated with the recombinant human TNFα receptor protein, etanercept. To the best of our knowledge this is the first report of NB successfully treated with etanercept.

Item Details

Item Type:Contribution to Refereed Journal
Keywords:neurology, diagnosis, treatment, inflammatory
Research Division:Biomedical and Clinical Sciences
Research Group:Neurosciences
Research Field:Central nervous system
Objective Division:Health
Objective Group:Clinical health
Objective Field:Treatment of human diseases and conditions
UTAS Author:Alty, JE (Associate Professor Jane Alty)
ID Code:145415
Year Published:2007
Web of Science® Times Cited:36
Deposited By:Wicking Dementia Research and Education Centre
Deposited On:2021-07-21
Last Modified:2021-08-06

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