Following the emergence of electronic cigarette, or vaping product use associated lung injury (EVALI) in 2019 in the US, regulation of e-cigarettes has become globally tighter and the collective evidence of the detrimental effects of vaping has grown. The danger of cellular distress and altered homeostasis is heavily associated with the modifiable nature of electronic cigarette devices. An array of harmful chemicals and elevated concentrations of metals have been detected in e-cigarette aerosols which have been linked to various pathogeneses. Vaping is linked to increased inflammation, altered lipid homeostasis and mitochondrial dysfunction whilst also increasing microbial susceptibility whilst the long-term damage is yet to be observed. The scientific evidence is mounting and highlighting that, along with traditional tobacco cigarette smoking, electronic cigarette vaping is not a safe practice.

Item Type:	Refereed Article
Keywords:	COVID-19, SARS-CoV-2, electronic cigarettes, IQOS, COPD, epithelium, fibrosis, EMT, Cancer, ICS, infections
Research Division:	Biomedical and Clinical Sciences
Research Group:	Cardiovascular medicine and haematology
Research Field:	Cardiology (incl. cardiovascular diseases)
Objective Division:	Health
Objective Group:	Clinical health
Objective Field:	Diagnosis of human diseases and conditions
UTAS Author:	McAlinden, KD (Mr Kielan McAlinden)
UTAS Author:	LU, W (Dr Monica Lu)
UTAS Author:	Eapen, MS (Dr Mathew Eapen)
UTAS Author:	Sohal, SS (Dr Sukhwinder Sohal)
ID Code:	145267
Year Published:	2021
Web of Science® Times Cited:	8
Deposited By:	Health Sciences
Deposited On:	2021-07-14
Last Modified:	2022-08-25
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