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Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression
Citation
Craig, JE and Han, X and Qassim, A and Hassall, M and Cooke Bailey, JN and Kinzy, TG and Khawaja, AP and An, J and Marshall, H and Gharahkhani, P and Igo, RP and Graham, SL and Healey, PR and Ong, JS and Zhou, T and Siggs, O and Law, MH and Souzeau, E and Ridge, B and Hysi, PG and Burdon, KP and Mills, RA and Landers, J and Ruddle, JB and Agar, A and Galanopoulos, A and White, AJR and Willoughby, CE and Andrew, NH and Best, S and Vincent, AL and Goldberg, I and Radford-Smith, G and Martin, NG and Montgomery, GW and Vitart, V and Hoehn, R and Wojciechowski, R and Jonas, JB and Aung, T and Pasquale, LR and Cree, AJ and Sivaprasad, S and Vallabh, NA and Viswanathan, AC and Pasutto, F and Haines, JL and Klaver, CCW and van Duijn, CM and Casson, RJ and Foster, PJ and Khaw, PT and Hammond, CJ and Mackey, DA and Mitchell, P and Lotery, AJ and Wiggs, JL and Hewitt, AW and MacGregor, S, NEIGHBORHOOD consortium and UK Biobank Eye and Vision Consortium, Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression, Nature Genetics, 52, (2) pp. 160-166. ISSN 1061-4036 (2020) [Refereed Article]
Copyright Statement
Copyright 2020
DOI: doi:10.1038/s41588-019-0556-y
Abstract
Item Details
Item Type: | Refereed Article |
---|---|
Keywords: | glaucoma, polygenic risk |
Research Division: | Biomedical and Clinical Sciences |
Research Group: | Ophthalmology and optometry |
Research Field: | Ophthalmology |
Objective Division: | Health |
Objective Group: | Clinical health |
Objective Field: | Diagnosis of human diseases and conditions |
UTAS Author: | Burdon, KP (Professor Kathryn Burdon) |
UTAS Author: | Mackey, DA (Professor David Mackey) |
UTAS Author: | Hewitt, AW (Professor Alex Hewitt) |
ID Code: | 144799 |
Year Published: | 2020 |
Web of Science® Times Cited: | 85 |
Deposited By: | Menzies Institute for Medical Research |
Deposited On: | 2021-06-11 |
Last Modified: | 2022-08-29 |
Downloads: | 0 |
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