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Evolving worldwide approaches to lipid management and implications for Australian general practice


Brett, T and Radford, J and Qureshi, N and Pang, J and Watts, GF, Evolving worldwide approaches to lipid management and implications for Australian general practice, Australian Journal of General Practice, 50, (5) pp. 297-304. ISSN 2208-7958 (2021) [Substantial Review]

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DOI: doi:10.31128/AJGP-06-20-5467


Background: Guidelines on lipid disorders are constantly evolving. General practitioners regularly face critical decisions about the best treatment strategies for individual patients. Cardiovascular disease (CVD) is common, with most morbidity and mortality due to atherosclerosis. Raised low-density lipoprotein cholesterol (LDL-C) is the most atherogenic component - lowering it lowers the risk of future cardiovascular events.

Objective: The aim of this article is to provide an evidence-informed summary of national guidelines and recent research to help clinicians reduce the risk of atherosclerotic CVD and improve health service delivery through improved lipid management strategies.

Discussion: Elevated plasma lipids, especially LDL-C, increase the likelihood of a CVD event over time. Knowledge of family and personal histories plus other risk factors for CVD should alert clinicians to the need for treatment. The greater the overall burden of combined risk factors, the greater the lifetime risk. This update provides new information that informs future approaches for improving lipid management in Australian general practice.

Item Details

Item Type:Substantial Review
Keywords:Familial Hypercholesterolaemia, general practice, preventive healthcare, atherosclerotic cardiovascular disease, cascade testing, genetic disease, screening
Research Division:Health Sciences
Research Group:Health services and systems
Research Field:General practice
Objective Division:Health
Objective Group:Provision of health and support services
Objective Field:Primary care
UTAS Author:Radford, J (Professor Jan Radford)
ID Code:144507
Year Published:2021
Deposited By:Medicine
Deposited On:2021-05-26
Last Modified:2021-05-27

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