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An open microfluidic chip for continuous sampling of solute from a turbulent particle suspension
journal contribution
posted on 2023-05-20, 22:50 authored by Shallan, AI, Tavares, Y, Navvab Kashani, M, Michael BreadmoreMichael Breadmore, Priest, CHigh solids content complicates in situ analysis of chemical processing, biological suspensions, and environmental streams. In most cases, analytical methods require at least one pre‐treatment step of a small volume of sample before a particle‐free fluid can be analyzed. We have developed a continuous in situ sampler that can "sip" particle‐free solution from a turbulent high solids content stream (a slurry). An open microfluidic chip with an extended slit opening shields the internal laminar flow from the turbulence outside. Unlike other open chips, our chip does not require close proximity to a solid surface and operates in turbulent environments for hours without maintenance. Two applications are demonstrated: monitoring FeIII in a stirred slurry of mixed ore particles at high solids loading (4 %wt) and paracetamol tablet dissolution profiles for two different formulations.
Funding
Department of Industry, Science, Energy and Resources
History
Publication title
Angewandte Chemie - International EditionVolume
60Issue
5Pagination
2654-2657ISSN
1433-7851Department/School
School of Natural SciencesPublisher
Wiley-V C H Verlag GmbhPlace of publication
Po Box 10 11 61, Weinheim, Germany, D-69451Rights statement
Copyright 2020 Wiley-VCH GmbHRepository Status
- Restricted