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An open microfluidic chip for continuous sampling of solute from a turbulent particle suspension


Shallan, AI and Tavares, Y and Navvab Kashani, M and Breadmore, MC and Priest, C, An open microfluidic chip for continuous sampling of solute from a turbulent particle suspension, Angewandte Chemie - International Edition, 60, (5) pp. 2654-2657. ISSN 1433-7851 (2021) [Refereed Article]

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Copyright 2020 Wiley-VCH GmbH

DOI: doi:10.1002/anie.202012410


High solids content complicates in situ analysis of chemical processing, biological suspensions, and environmental streams. In most cases, analytical methods require at least one pre‐treatment step of a small volume of sample before a particle‐free fluid can be analyzed. We have developed a continuous in situ sampler that can "sip" particle‐free solution from a turbulent high solids content stream (a slurry). An open microfluidic chip with an extended slit opening shields the internal laminar flow from the turbulence outside. Unlike other open chips, our chip does not require close proximity to a solid surface and operates in turbulent environments for hours without maintenance. Two applications are demonstrated: monitoring FeIII in a stirred slurry of mixed ore particles at high solids loading (4 %wt) and paracetamol tablet dissolution profiles for two different formulations.

Item Details

Item Type:Refereed Article
Keywords:analytical chemistry
Research Division:Chemical Sciences
Research Group:Analytical chemistry
Research Field:Separation science
Objective Division:Expanding Knowledge
Objective Group:Expanding knowledge
Objective Field:Expanding knowledge in the chemical sciences
UTAS Author:Breadmore, MC (Professor Michael Breadmore)
ID Code:143976
Year Published:2021
Web of Science® Times Cited:2
Deposited By:Chemistry
Deposited On:2021-04-13
Last Modified:2022-08-26

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