eCite Digital Repository

The influence of exercise intensity and exercise mode on gastrointestinal damage

Citation

Edwards, K and Ahuja, KD and Watson, G and Dowling, C and Musgrave, H and Reyes, J and Cherry, J and Kitic, CM, The influence of exercise intensity and exercise mode on gastrointestinal damage, Applied Physiology, Nutrition, and Metabolism ISSN 1715-5312 (2021) [Refereed Article]

PDF (Accepted version)
498Kb
  

Copyright Statement

Copyright unknown

DOI: doi:10.1139/apnm-2020-0883

Abstract

Strenuous exercise increases gastrointestinal damage, but the dose-response relationship is yet to be elucidated. It is also commonly believed that running causes greater gastrointestinal damage than cycling. Two randomised, cross-over studies aimed to 1) quantify gastrointestinal damage with increasing exercise intensity, and 2) determine if running was associated with greater gastrointestinal damage than cycling. Following a V̇O2max test, participants completed three cycling trials at different intensities (60min at 40%, 60% and 80% V̇O2max; n=10 (5 female, 5 male)) (INTENSITY), or one running and one cycling trial (45min at 70% V̇O2max; n=11 (3 female, 8 male)) (MODE). Venous blood samples were collected pre- and post- exercise to measure gastrointestinal damage via intestinal fatty acid binding protein (I-FABP). In INTENSITY, I-FABP magnitude of change was greater at 80% V̇O2max than 40% V̇O2max (p<0.01). In MODE, I-FABP magnitude of change was greater with cycling (mean (SD)) (84.7 (133.2)% d=1.07) compared to running (19.3 (33.1)%, d=0.65) with a moderate effect (d=0.68, p=0.024). RPE and HR were higher during cycling (RPE p<0.0001; HR p<0.0001) but rectal temperature was not different between modes (p=0.94). While gastrointestinal damage increases with increasing exercise intensity, running was not associated with greater gastrointestinal damage than cycling. Novelty Bullets: •A fraction of the anaerobic threshold, rather than a fraction of V̇O2max, may be more predictive of intensity that results in exercise induced gastrointestinal damage •The mode of exercise may not be as important as intensity for inducing gastrointestinal damage •Improving anaerobic threshold may reduce susceptibility to gastrointestinal damage when exercising at high intensities.

Item Details

Item Type:Refereed Article
Keywords:I-FABP, gut, intestinal damage, exercise, running, cycling, intensity
Research Division:Health Sciences
Research Group:Sports science and exercise
Research Field:Exercise physiology
Objective Division:Culture and Society
Objective Group:Sport, exercise and recreation
Objective Field:Exercise
UTAS Author:Edwards, K (Ms Kate Edwards)
UTAS Author:Ahuja, KD (Dr Kiran Ahuja)
UTAS Author:Watson, G (Dr Greig Watson)
UTAS Author:Dowling, C (Miss Courtney Dowling)
UTAS Author:Reyes, J (Mrs Jess Reyes)
UTAS Author:Kitic, CM (Dr Cecilia Kitic)
ID Code:143568
Year Published:2021
Deposited By:Health Sciences
Deposited On:2021-03-24
Last Modified:2021-06-30
Downloads:8 View Download Statistics

Repository Staff Only: item control page