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Anodal transcranial direct current stimulation over the ventromedial prefrontal cortex enhances fear extinction in healthy humans: a single blind sham-controlled study

Citation

Vicario, CM and Nitsche, MA and Hoysted, I and Yavari, F and Avenanti, A and Salehinejad, MA and Felmingham, KL, Anodal transcranial direct current stimulation over the ventromedial prefrontal cortex enhances fear extinction in healthy humans: a single blind sham-controlled study, Brain stimulation, 13, (2, March-April) pp. 489-491. ISSN 1935-861X (2020) [Refereed Article]


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Copyright 2019 Elsevier Inc. Licensed under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) https://creativecommons.org/licenses/by-nc-nd/4.0/

Official URL: https://www.sciencedirect.com/science/article/pii/...

DOI: doi:10.1016/j.brs.2019.12.022

Abstract

Anxiety disorders are among the most common mental disorders [1,2]. Fear extinction is considered essential to promote successful treatment of several anxiety disorders. Neuroscience research has provided evidence for the contribution of the ventromedial prefrontal cortex (vmPFC) in extinction learning and recall [3,4]. Its role in fear extinction has been investigated via transcranial direct current stimulation (tDCS) in a recent sham-controlled study involving healthy participants. In that study [5], 5 minutes of 2 mA anodal stimulation over the left vmPFC during fear extinction reduced the physiological expression of fear (reduction of Skin conductance response - SCR) induced via Pavlovian conditioning. However, no effects were reported for the recall session.

Item Details

Item Type:Refereed Article
Research Division:Biomedical and Clinical Sciences
Research Group:Neurosciences
Research Field:Neurosciences not elsewhere classified
Objective Division:Health
Objective Group:Public health (excl. specific population health)
Objective Field:Mental health
UTAS Author:Vicario, CM (Dr Carmelo Vicario)
UTAS Author:Hoysted, I (Miss Hoysted)
ID Code:143034
Year Published:2020
Web of Science® Times Cited:12
Deposited By:Psychology
Deposited On:2021-02-23
Last Modified:2021-05-26
Downloads:6 View Download Statistics

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