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Non-adherence to thromboprophylaxis guidelines in Atrial fibrillation: a narrative review of the extent of and factors in guideline non-adherence

Citation

Gebreyohannes, EA and Salter, S and Chalmers, L and Bereznicki, L and Lee, KJ, Non-adherence to thromboprophylaxis guidelines in Atrial fibrillation: a narrative review of the extent of and factors in guideline non-adherence, American Journal of Cardiovascular Drugs ISSN 1175-3277 (2020) [Refereed Article]

Copyright Statement

Copyright 2020 Springer Nature Switzerland AG

Official URL: https://link.springer.com/article/10.1007%2Fs40256...

DOI: doi:10.1007/s40256-020-00457-3

Abstract

Atrial fibrillation is the most common arrhythmia. It increases the risk of thromboembolism by up to fivefold. Guidelines provide evidence-based recommendations to effectively mitigate thromboembolic events using oral anticoagulants while minimizing the risk of bleeding. This review focuses on non-adherence to contemporary guidelines and the factors associated with guideline non-adherence. The extent of guideline non-adherence differs according to geographic region, healthcare setting, and risk stratification tools used. Guideline adherence has gradually improved over recent years, but a significant proportion of patients are still not receiving guideline-recommended therapy. Physician-related and patient-related factors (such as patient refusals, bleeding risk, older age, and recurrent falls) also contribute to guideline non-adherence, especially to undertreatment. Quality improvement initiatives that focus on undertreatment, especially in the primary healthcare setting, may help to improve guideline adherence.

Item Details

Item Type:Refereed Article
Keywords:non-adherence, thromboprophylaxis, atrial fibrillation, review
Research Division:Biomedical and Clinical Sciences
Research Group:Pharmacology and pharmaceutical sciences
Research Field:Pharmaceutical sciences
Objective Division:Health
Objective Group:Other health
Objective Field:Other health not elsewhere classified
UTAS Author:Bereznicki, L (Professor Luke Bereznicki)
UTAS Author:Lee, KJ (Dr Kenneth Lee)
ID Code:143025
Year Published:2020
Web of Science® Times Cited:2
Deposited By:Pharmacy
Deposited On:2021-02-23
Last Modified:2021-05-11
Downloads:0

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