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Correlates of indicators of potential extra-medical opioid use in people prescribed opioids for chronic non-cancer pain
Citation
Santo JR, T and Larance, B and Bruno, R and Gisev, N and Nielsen, S and Degenhardt, L and Campbell, G, Correlates of indicators of potential extra-medical opioid use in people prescribed opioids for chronic non-cancer pain, Drug and Alcohol Review, 39, (2) pp. 128-134. ISSN 0959-5236 (2020) [Refereed Article]
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Abstract
Introduction and Aims. The opioid-related behaviours in treatment (ORBIT) scale are a measure of recent indicators of
potential extra-medical opioid use. Indicators of potential extra-medical opioid use are divergent practices among people
prescribed opioids that may place them at risk of harm. This study aimed to examine the correlates of indicators of potential
extra-medical opioid use in people prescribed opioids for chronic non-cancer pain (CNCP). Design and Methods. The Pain
and Opioids IN Treatment (POINT) study is a prospective cohort study of people prescribed opioids for CNCP in Australia.
People prescribed opioids solely for opioid dependence were excluded. This cross-sectional study utilised logistic regression to
determine the characteristics associated with reporting any indicators of potential extra-medical opioid use.
Results. Of the
1505 participants, 38% reported at least one indicator of potential extra-medical opioid use, most commonly asking for an
increase in prescribed opioid dose (21%) and early prescription renewal (12%). Indicators of potential extra-medical opioid
use were associated with younger age (adjusted odds ratio [AOR] = 0.98; 95% confidence interval [CI] = 0.92, 0.99), male
sex (AOR = 1.53; 95% CI = 1.15, 2.04), lifetime pharmaceutical opioid use disorder (AOR = 1.87; 95% CI = 1.31,
2.66) and lifetime illicit drug use disorder (AOR = 1.72; 95% CI = 1.18, 2.52).
Discussion and Conclusions. Over
one-third of the POINT cohort reported one or more indicators of potential extra-medical opioid use. Lifetime substance use
disorders were associated these divergent practices, highlighting the importance of clinical monitoring and patient education for
this patient group. Longitudinal studies are needed to investigate whether indicators of potential extra-medical opioid use
predict opioid use disorders in this population.
Item Details
| Item Type: | Refereed Article |
|---|---|
| Keywords: | pharmaceutical opioid dependence, chronic pain, opioid analgesics, addiction, medication adherence, pain management |
| Research Division: | Psychology |
| Research Group: | Clinical and health psychology |
| Research Field: | Health psychology |
| Objective Division: | Health |
| Objective Group: | Public health (excl. specific population health) |
| Objective Field: | Substance abuse |
| UTAS Author: | Bruno, R (Associate Professor Raimondo Bruno) |
| ID Code: | 142490 |
| Year Published: | 2020 |
| Deposited By: | Psychology |
| Deposited On: | 2021-01-19 |
| Last Modified: | 2021-01-20 |
| Downloads: | 0 |
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