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Association between influenza vaccine administration and primary care consultations for respiratory infections: Sentinel network study of five seasons (2014/20152018/2019) in the UK

Citation

Parimalanathan, V and Joy, M and Van Dam, PJ and Fan, X and de Lusignan, S, Association between influenza vaccine administration and primary care consultations for respiratory infections: Sentinel network study of five seasons (2014/2015-2018/2019) in the UK, International Journal of Environmental Research and Public Health, 18, (2) pp. 1-13. ISSN 1660-4601 (2021) [Refereed Article]


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Copyright 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).

DOI: doi:10.3390/ijerph18020523

Abstract

Influenza, a vaccine preventable disease, is a serious global public health concern which results in a considerable burden on the healthcare system. However, vaccine hesitancy is increasingly becoming a global problem. One prevalent misconception is that influenza vaccinations can cause the flu. We carried out this study to determine whether people undertaking influenza vaccination presented less with acute respiratory tract infection (ARTI) and influenza-like-illness (ILI) following vaccination. We utilised the Oxford Royal College of General Practitioners Research and Surveillance Centre sentinel database to examine English patients who received vaccination between 2014/2015 and 2018/2019. Of the 3,841,700 influenza vaccinations identified, vaccination details and primary care respiratory consultation counts were extracted to calculate the relative incidence (RI) per exposure risk period using the self-controlled case series methodology. Results showed a significant increase in the RI of respiratory consultation rates within fourteen days of vaccination across all five years. Less than 6.2% of vaccinations led to consultations for ARTI or ILI in primary care (crude consultation rate 6196 per 100,000). These findings, particularly if confirmed in further research, may reduce the risk of cross-infection between waiting patients and increase uptake of influenza vaccine.

Item Details

Item Type:Refereed Article
Keywords:influenza vaccine, general practice, vaccine hesitancy, primary care
Research Division:Health Sciences
Research Group:Public health
Research Field:Preventative health care
Objective Division:Health
Objective Group:Provision of health and support services
Objective Field:Primary care
UTAS Author:Parimalanathan, V (Dr Vaishnavi Parimalanathan)
UTAS Author:Van Dam, PJ (Dr Pieter Van Dam)
ID Code:142338
Year Published:2021
Deposited By:Medicine
Deposited On:2021-01-11
Last Modified:2021-02-12
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