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Association between influenza vaccine administration and primary care consultations for respiratory infections: Sentinel network study of five seasons (2014/2015–2018/2019) in the UK
Citation
Parimalanathan, V and Joy, M and Van Dam, PJ and Fan, X and de Lusignan, S, Association between influenza vaccine administration and primary care consultations for respiratory infections: Sentinel network study of five seasons (2014/2015-2018/2019) in the UK, International Journal of Environmental Research and Public Health, 18, (2) pp. 1-13. ISSN 1660-4601 (2021) [Refereed Article]
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Copyright Statement
Copyright 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
DOI: doi:10.3390/ijerph18020523
Abstract
Influenza, a vaccine preventable disease, is a serious global public health concern which
results in a considerable burden on the healthcare system. However, vaccine hesitancy is increasingly
becoming a global problem. One prevalent misconception is that influenza vaccinations can cause
the flu. We carried out this study to determine whether people undertaking influenza vaccination
presented less with acute respiratory tract infection (ARTI) and influenza-like-illness (ILI) following
vaccination. We utilised the Oxford Royal College of General Practitioners Research and Surveillance
Centre sentinel database to examine English patients who received vaccination between 2014/2015
and 2018/2019. Of the 3,841,700 influenza vaccinations identified, vaccination details and primary
care respiratory consultation counts were extracted to calculate the relative incidence (RI) per exposure risk period using the self-controlled case series methodology. Results showed a significant
increase in the RI of respiratory consultation rates within fourteen days of vaccination across all five
years. Less than 6.2% of vaccinations led to consultations for ARTI or ILI in primary care (crude
consultation rate 6196 per 100,000). These findings, particularly if confirmed in further research, may
reduce the risk of cross-infection between waiting patients and increase uptake of influenza vaccine.
Item Details
Item Type: | Refereed Article |
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Keywords: | influenza vaccine, general practice, vaccine hesitancy, primary care |
Research Division: | Health Sciences |
Research Group: | Public health |
Research Field: | Preventative health care |
Objective Division: | Health |
Objective Group: | Provision of health and support services |
Objective Field: | Primary care |
UTAS Author: | Parimalanathan, V (Dr Vaishnavi Parimalanathan) |
UTAS Author: | Van Dam, PJ (Dr Pieter Van Dam) |
ID Code: | 142338 |
Year Published: | 2021 |
Deposited By: | Medicine |
Deposited On: | 2021-01-11 |
Last Modified: | 2021-02-12 |
Downloads: | 24 View Download Statistics |
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